Nevertheless, when the homeostatic balance between prooxidant and antioxidant system in the plasma and endothelial cells is disturbed for a relatively long period, nLDL as well as modified LDL, such as oxLDL, could induce the premature senescence
of vascular endothelial cells.
Therefore, we further investigated the effects of GlcN on H[sub]2O[sub]2-induced premature senescence
in human RPE cells by SA-[sz]-Gal staining.
Goligorsky, "Stress-induced premature senescence
of endothelial cells," Journal of Nephrology, vol.
of cotton (Gossypium hirsutum L.) predominantly a potassium disorder caused by an imbalance of source and sink.
Hyperoxia-induced premature senescence
requires p53 and pRb, but not mitochondrial matrix ROS.
Yun, "Nek6 suppresses the premature senescence
of human cancer cells induced by camptothecin and doxorubicin treatment," Biochemical and Biophysical Research Communications, vol.
Sustained inhibition of oxidative phosphorylation impairs cell proliferation and induces premature senescence
in human fibroblasts.
(PS) occurs frequently in cotton crops in Australia.
Mapping of post-flowering drought resistance traits in grain sorghum: Association between QTLs influencing premature senescence
And Charles Mudd-Gaddis, a victim of progeria, premature senescence
, is an 8-year-old dying of old age.
These studies demonstrate that native low-density lipoprotein (LDL) or serum from varicose patients induces premature senescence
of endothelial cells (HUVECs), with both treatments leading to the generation of reactive oxygen species (ROS).
Our previous studies performed with the same SHS induction design demonstrated that SHS triggered premature senescence
of eMSC in culture.