Nevertheless, when the homeostatic balance between prooxidant and antioxidant system in the plasma and endothelial cells is disturbed for a relatively long period, nLDL as well as modified LDL, such as oxLDL, could induce the
premature senescence of vascular endothelial cells.
Therefore, we further investigated the effects of GlcN on H[sub]2O[sub]2-induced
premature senescence in human RPE cells by SA-[sz]-Gal staining.
Goligorsky, "Stress-induced
premature senescence of endothelial cells," Journal of Nephrology, vol.
Premature senescence of cotton (Gossypium hirsutum L.) predominantly a potassium disorder caused by an imbalance of source and sink.
Hyperoxia-induced
premature senescence requires p53 and pRb, but not mitochondrial matrix ROS.
Yun, "Nek6 suppresses the
premature senescence of human cancer cells induced by camptothecin and doxorubicin treatment," Biochemical and Biophysical Research Communications, vol.
Sustained inhibition of oxidative phosphorylation impairs cell proliferation and induces
premature senescence in human fibroblasts.
Premature senescence (PS) occurs frequently in cotton crops in Australia.
Mapping of post-flowering drought resistance traits in grain sorghum: Association between QTLs influencing
premature senescence and maturity.
And Charles Mudd-Gaddis, a victim of progeria,
premature senescence, is an 8-year-old dying of old age.
These studies demonstrate that native low-density lipoprotein (LDL) or serum from varicose patients induces
premature senescence of endothelial cells (HUVECs), with both treatments leading to the generation of reactive oxygen species (ROS).
Our previous studies performed with the same SHS induction design demonstrated that SHS triggered
premature senescence of eMSC in culture.