Long before symptoms of schizophrenia can be detected, for example, there may be some evidence of reduced cognitive functioning, a period of "prepsychotic
disturbance" (Yung & McGorry, 1996, p.
Higher levels of those, still at a prepsychotic
level, but at a higher, prodromal level of activity, predicts psychosis with pretty high accuracy on their own," he said.
The diagnoses suspected by the psychiatrists were "reactive depression, prepsychotic
personality, obsessive-compulsive disorder, narcissistic personality disorder" and he was started on many antidepressants and antipsychotics.
On the other hand, TMZ, as an anti-oxidant and cytoprotective agent, can be useful in neuroprotection especially on early stages of psychosis or prepsychotic
patients with insignificant symptoms.
DR NASRALLAH: Dr Muzina, did you feel that this patient exhibited some psychotic or prepsychotic
Schizophrenia occurs in all ethnic and racial groups and in all social classes. The disease progresses from subtle premorbid symptoms during childhood, through an early (ie, prodomal) phase, to prepsychotic
and full-blown psychosis phases.
Table 3 International clinical practice guidelines for the prepsychotic
Treatment with antidepressants kept adolescent patients in the prepsychotic
phase of schizophrenia from progressing to full psychosis or bipolar disorder more effectively than did treatment with antipsychotics, said Barbara A.