primaquine


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primaquine

[′prī·mə‚kwēn]
(pharmacology)
C15H21N3O An ether-soluble viscous liquid, used as the diphosphate salt in medicine to cure malaria.
References in periodicals archive ?
CDC recommends a primaquine phosphate dose of 30 mg (base) by mouth daily for 14 days.
This finding prompted mass treatment with chloroquine and primaquine of 203 persons within that community.
% Parasitemia 7% -- Polymerase chain N/A Plasmodium reaction (PCR) ovale Hematocrit 29% 30% Platelets 59,000 210,000 Aspartate 68 118 aminotransferase Alanine 43 150 aminotransferase [P.sub.a][O.sub.2] 49 -- ([section]) Treatment Predeparture sulfadoxine artemether- pyrimethamine lumefantrine In the United atovaquone- mefloquine and States proguanil primaquine Characteristic Case 3 Case 4 Patient age (yrs) 6 6 Sex Male Male Arrival in United July 23, 2007 September 28, 2007 States Symptom onset August 13, 2007 October 1, 2007 Signs/Symptoms Fever, headache, Fever, cough malaise Laboratory findings Blood smear Plasmodium spp.
The malaria control programme in KZN added a single dose of primaquine to SP in the mid-1990s, to reduce transmission.
Primaquine also is the only drug that's effective for terminal prophylaxis, to prevent infection of people who have heavy exposure to the relapsing strains of Plasmodium vivax, P.
The true deficiency of G6PD was identified initially in the middle of the last century, in black race North americans during the investigations carried out over the hemolytic effect of the primaquine (19).
Eligible Congolese refugees with splenomegaly should be treated with primaquine, followed closely, and referred for specialty care if they fail to respond to treatment, and their family members should be proactively screened for splenomegaly.
Pilots should aim to enable the adoption of radical cure tools in target countries and provide a roadmap for the optimal deployment of G6PD testing, primaquine and tafenoquine, more broadly.
Safety of primaquine given to people with G6PD deficiency: Systematic review of prospective studies.
In a related primaquine dosing study, the relapse rate for 3 vivax strains was compared, but relapse time was not examined (13).
Patient 1 received additional treatment with primaquine to prevent relapse of P.
The patient was given primaquine for 14 days for radical cure.