primary biliary cirrhosis


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Related to primary biliary cirrhosis: secondary biliary cirrhosis, Primary sclerosing cholangitis

primary biliary cirrhosis

[¦Prīm·ə·rē ‚bil·ē·er·ē sə′rō·səs]
(medicine)
A slowly progressive disease primarily of middle-aged women, caused by an autoimmune destruction of bile ducts that begins as inflammation in and around larger intrahepatic bile ducts and eventually results in liver cell damage.
References in periodicals archive ?
Furthermore, case reports show that tamoxifen, an antiestrogen, improves liver biochemistry in primary biliary cirrhosis," the investigators said.
Primary biliary cirrhosis is a rare disease of unknown cause that results in the loss of functioning liver cells and an increased resistance to blood flow through the liver.
A snapshot of the global therapeutic scenario for Primary Biliary Cirrhosis.
Patients should undergo surveillance for HCC if they have cirrhosis secondary to the following conditions: hepatitis B, hepatitis C, stage 4 primary biliary cirrhosis, genetic hemochromatosis, and alpha 1 antitrypsin deficiency.
Research involving 5000 people suggested smokers are 63 per cent more likely to suffer from potentially lethal primary biliary cirrhosis of the liver.
Medics at the Freeman Hospital and the Royal Victoria Infirmary will now be able to continue their research into liver disease primary biliary cirrhosis in the hope of finding its cause and improving the symptoms for patients.
The money will go to the Primary Biliary Cirrhosis Foundation and I know John would be so proud that you donated so much money to his memory.
An inverse association between the TNF-[alpha] -308A allele and disease manifestation was found in Gaucher disease (30) and primary biliary cirrhosis (31, 32).
The first volume contains articles on mediators and regulation of liver disease and the immunological basis of liver injury, with individual topics that include the role of chemokines in liver pathophysiology, the basis for immune recognition of cellular targets in primary biliary cirrhosis, and the role of nitric oxide in liver disorders.
Secondary causes of low BMD include endocrinopathies (hypercalciuria, hypogonadism, hyper-parathyroidism, and Cushing's syndrome), some GI disorders (gastrectomy, inflammatory bowel disease, celiac disease, intestinal bypass surgery, primary biliary cirrhosis, and pancreatic insufficiency), genetic disorders (Ehlers-Danlos syndrome, Marfan syndrome, and homocystinuria), and eating disorders (anorexia nervosa, bulimia nervosa, and female athlete triad).
The association between celiac sprue and liver disease other than primary biliary cirrhosis, autoimmune hepatitis, or primary sclerosing cholangitis is not generally recognized.
Furthermore, one should look for destructive cholangitis associated with primary biliary cirrhosis or interface hepatitis (piecemeal necrosis) around lymphoid nodules with varying degrees of portal fibrosis in cases of chronic hepatitis B or C infection.