Prodromal Period


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Prodromal Period

 

the period during which premonitory symptoms of a disease or condition appear. In the prodromal period of infections, the symptoms may be nonspecific, such as weakness, headache, and mild fever, or specific, for example, the spots on the buccal mucosa in measles (the Bel’skii-Filatov-Koplik symptom, or Koplik’s spots); laboratory test results reveal changes in the body. The prodromal period is preceded by the incubation period, during which there are no symptoms despite the infection. It is followed by a period of a developed clinical picture of the disease.

The prodromal period may also be observed in some noninfectious diseases. Thus, in the period preceding myocardial infarction, an increase in the frequency and severity of attacks of angina pectoris is observed, and changes in the cellular composition of the bone marrow are observed before the onset of leukemia.

References in periodicals archive ?
(6,7) in this study we sought to use iVCM to elucidate corneal alterations that begin in the prodromal period of EKC, evaluate findings seen in the clinical course of the disease, and discuss our results within the context of the literature.
On the other hand, it is suggested that the patients with PD in the prodromal period may also have an increased risk of falls.
TEN presents with a prodromal period mimicking an upper respiratory tract infection, followed by poorly defined erythematous macules or diffuse ill-defined erythema.
19 years, respectively; P less than .05), yet they did not differ significantly in duration of the prodromal period. Patients with a first-degree FH of psychosis also had a significantly younger age at onset of psychosis, compared with those who had no such FH (mean age, 18 vs.
Silent thyroiditis constituting approximately 1% all of thyroiditis cases (1) is distinguished from postpartum thyroiditis by the absence of postpartum period (2), and from subacute thyroiditis by the absence of a viral prodromal period and pain or tenderness in physical examination (3).
For Canon John Hill, a retired priest in Toronto, Lent is a prodromal period of confession, admission and rededication leading up to the crucifixion.
With regard to specific symptoms in the prodromal period, men were more likely than women to report weakness or clumsiness (50% men versus 37% women, p = .008).
Stage 0, which was added later by Shibata et al., is a prodromal period initiated by trauma but without any significant radiographic findings.
If there is a prodromal period of insomnia before depressive symptoms emerge, more ecologically valid measures are needed to assess this relationship.
As the prodromal period at this point can only truly be identified in retrospect, we need to be cautious in identifying candidates for early intervention.
To reconstruct, rather than explain, the prodromal period leading up to the first episode of depression in a group of adolescents with first episode depression.