prodrug


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prodrug

[′prō‚drəg]
(physiology)
An inactive precursor of a drug that is activated via the body's metabolism.
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CLX-103 is a novel, patented prodrug molecular conjugate of mesalamine, eicosapentaenoic acid and caprylic acid designed to offer incremental benefits over the currently approved 5-ASA formulations for the treatment of ulcerative colitis.
M2 EQUITYBITES-July 13, 2017-Biohaven awarded US Notice Of Allowance for patent for glutamate modulating prodrugs
Recently, macromolecular prodrug design (MPDD) and applications based on etherified renewable polysaccharides especially cellulose, e.
It is based on a prodrug with four components: the actual cytotoxic agent, a ligand that recognizes one of the tumor-specific receptors, a "trigger" for the release, and a linker that holds everything together.
The day's big winner, Cascade Prodrug, was founded in September 2009 by biotech veterans Allan Cochrane and Augie Sick.
A prodrug is an inactive precursor of a drug that is converted into its active form in the body by normal metabolic processes.
The compound covered under this agreement has improved solubility and bioavailability after converted to a dihydrogen phosphonoxy methoxy derivative modified prodrug.
Fenethylline, also spelled Phenethylline and marketed under the brand name Captagon, is a synthetic prodrug used as a stimulant.
As a therapeutically inactive prodrug, Vyvanse contains D-amphetamine bonded covalently to I-lysine and is converted to pharmacologically active D-amphetamine after oral ingestion.
Chicago -- An investigational gabapentin prodrug may be an effective therapy for symptoms and sleep problems associated with restless legs syndrome, Dr.
XP13512 is a new chemical entity that is a Transported Prodrug of gabapentin, an agent indicated for the treatment of seizure and neuropathic pain.
This patent covers Semafore's lead clinical candidate, SF1126, and other prodrug compositions of the widely studied PI3K inhibitor, LY294002, that Semafore is evaluating as a novel therapy for cancer and other diseases.