pronormoblast

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pronormoblast

[prō′nȯr·mə‚blast]
(histology)
A nucleated erythrocyte precursor with scanty basophilic cytoplasm without hemoglobin. Also known as lymphoid hemoblast of Pappenheim; macroblast of Naegeli; megaloblast of Sabin; proerythroblast of Ferrata; prorubricyte; rubriblast; rubricyte.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
The erythropoiesis in bone marrow was lowered by inflammatory cytokines, the process of which was mainly resulted from the blockage of erythroid progenitor cell proliferation and proerythroblast maturation.
It is obvious that, unlike the erythrocyte, proerythroblast has a ripple profilogram in the central region, due to the presence of heterodispersed polymorphic granules.
Consequently, it is critical for iron to be available to the developing erythrocyte during the 3day window in which the proerythroblast develops into the reticulocyte.
The first RBC precursor, called the "proerythroblast," divides, develops, and eventually becomes filled with hemoglobin.
Erythroid differentiation started with the expression of CD71 (22.8% [CD71.sup.+]/[Ter119.sup.-] KO versus 27.9% [CD71.sup.+]/[Ter119.sup.-] NTC cells) in the proerythroblasts. The maturation into early erythroblast cells was indicated by [CD71.sup.high]/[Ter119.sup.-] expression (1.4% KO versus 2.7% NTC), and late erythroblasts cells expressed [CD71.sup.high]/[Ter119.sup.+] (2.3% KO versus 4.9% NTC).
Supplementary Figure 1: Representative cytospin images of proerythroblasts (Pro-E), basophilic erythroblasts (Baso-E), polychromatic erythroblasts (Poly-E), orthochromatic erythroblasts (Ortho-E), and mature erythrocytes.