24) Given the benefits of lactation to both infant and maternal health, (25,26) and the fact that the LNG-IUS carries a much lower systemic dose of progestin than the injectable, further study of how timing of initiation of progestin-only contraceptives
affects women's abilities to meet lactation recommendations (27) is urgently needed.
In addition to Agile's lead, advanced-stage program to develop AG200-15, the Company also is developing a low-dose, progestin-only contraceptive
Micronor, a progestin-only contraceptive
, works in a significant number of patients by preventing the implantation of a fertilized egg.
The once-weekly dosing regimen of the patch could help improve compliance and convenience in progestin-only contraceptive
Larger long-term, randomized, controlled studies that focus on weight and enroll users and nonusers who are otherwise comparable are still needed to definitively address the question of whether the high-dose progestin-only contraceptive
causes weight gain, said Dr.
Once-weekly dosing with the patch may improve compliance and convenience in progestin-only contraceptive
users, as well as provide more consistent average plasma norethindrone levels than oral progestin-only products.
By contrast, the product labeling for Depo-Provera states that about 68% of women who do become pregnant after discontinuing the injectable high-dose progestin-only contraceptive
may conceive within 12 months.
pills (POPs) are used as a routine method of birth control over longer periods of time, and are contraindicated in some conditions.
As with any progestin-only contraceptive
, users of IMPLANON(TM) can experience irregular bleeding.