prometaphase


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prometaphase

[prō′med·ə‚fāz]
(cell and molecular biology)
A stage between prophase and metaphase in mitosis in which the nuclear membrane disappears and the spindle forms.
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At prometaphase, 18S-25S rDNA sites also arrange peripherically and adjacent to each other (Fig.
PI, prophase I; PMI, prometaphase I; MI, metaphase I; MII, metaphase II; Egr3, early growth response protein 3; GV, germinal vesicle; IBMX, 3-isobutyl-1-methylxanthine.
role of cyclin Bl/Cdc2 up-regulation in the induction of mitotic prometaphase arrest in human breast cancer cells treated with 2-methoxyestradiol.
These stages are prophase, prometaphase, metaphase, anaphase, and telophase.
Mitotic Index (MI): the number of cells in mitosis (prophase + prometaphase + metaphase + anaphase + telophase) were divided by the total number of cells (interphase + mitosis) and multiplied by 100 (PIRES et al.
In prometaphase I, the poles of the QMS converge in pairs toward the spindle axis (Fig.
The purpose of use of colchicine in this research was to determine the possible existence of numerical and structural changes in the chromosomal set of meristimatical cells stopping mitosis in prometaphase.
The Caenorhabditis elegans kinetochore reorganizes at prometaphase and in response to checkpoint stimuli.
Activation of a novel ataxia-telangiectasia mutated and Rad3 related/checkpoint kinase 1-dependent prometaphase checkpoint in cancer cells by diallyl trisulfide, a promising cancer chemopreventive constituent of processed garlic.
These studies allowed us to gain deep knowledge on such important problems as: attachment of kinetochores to the spindle, kinetochore orientation and re-orientation during prometaphase I and metaphase I, in vivo orientation and segregation of the X chromosome, autosomal univalents, multiple chromosomal configurations (e.
Chromosome plates of prometaphase and metaphase II consist of bibrachial (meta- or submetacentric) and monobrachial chromosomes of different sizes (Fig.
CENP-E is also essential for prometaphase chromosome movements that contribute to metaphase chromosome alignment.