Health care company Bayer revealed on Friday the receipt of approval from the US Food and Drug Administration (FDA) for Jivi for the routine prophylactic treatment
of hemophilia A.
was used most commonly in the hematology ward (25%).
In addition, increasing prophylactic treatment
for hemophilia across the globe is further expected to drive the growth of this market.
The constant delivery of factor VIII is also expected to reduce or eliminate the need for multiple weekly infusions, which is the current standard of care using plasma-derived or recombinant, genetically engineered factor VIII for the prophylactic treatment
of hemophilia A.
Biofeedback and tricyclic antidepressants appear to be effective as prophylactic treatment
for chronic tension headaches, although tricyclic antidepressants have more adverse effects (strength of recommendation [SOR]: B, meta-analysis of randomized controlled trials [RCTs] and prepost trials).
However, in the absence of symptoms, prophylactic treatment
is controversial and is not supported by robust evidence.
The target is working on developing and commercialising Aes-103, an investigational prophylactic treatment
for SCD that is currently in a phase 2 clinical trial.
Recommending and encouraging lifestyle changes (increased fluid intake; avoid excessive salt, calcium, protein, and vitamin intake) and prophylactic treatment
with agents that alkalinize the urine may prevent this condition from recurring.
There is no prophylactic treatment
required in most of the cases as of now.
The good news is that the molecular tweezers appear to have a high safety margin, so they may be suitable for prophylactic treatment
starting long before the onset of the disease," he said.
In stark contrast to above body of evidences, a study revealed that prophylactic Vancomycin was effective in prevention of sepsis in pre term neonates with central venous catheters.10 Interestingly, another study showed that even in asymptomatic neonates, morbidity and mortality is increased if the prophylactic treatment
is not started timely.6