propylthiouracil


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propylthiouracil

[‚prō·pəl¦thī·ō′yu̇r·ə‚sil]
(pharmacology)
C7H10N2OS White, crystalline powder with a melting point of 218-221°C; soluble in ammonia and alkali hydroxides; used in medicine.
References in periodicals archive ?
Bass, "Single daily dose of methimazole compared to every 8 hours propylthiouracil in the treatment of hyperthyroidism," Southern Medical Journal, vol.
Propylthiouracil inhibits thyroid hormone synthesis and peripheral transformation of T4 to T3 and is given orally three times a day at a dose of 0.2-0.5 mg/kg/day.
BW: body weight; VW: ventricular weight; DEO: day of eye opening; [T.sub.4]: thyroxine; [T.sub.3]: triiodothyronine; PTU: propylthiouracil. *P<0.05, #P 0.01, +P<0.001 compared with control group (ANOvA).
Treatment with propylthiouracil is associated with appearance of antineutrophil cytoplasmic antibodies in some patients with Graves' disease.
Both classes of antithyroid agents, Propylthiouracil and Carbimazole, can cause liver dysfunction, which is among the small number of their idiosyncratic toxic effects.
In order to evaluate the applicability of the proposed method, the commercial medicinal sample containing 2-thiouracil from Propylthiouracil, India, was studied.
Thiamazole (MMI) and propylthiouracil (PTU) are antithyroid drugs (ATDs) that are used to treat GD.
He was treated with propylthiouracil and oral prednisone 140 mg/day) for thyrotoxicosis.
Goodman, "A controlled trial of topical propylthiouracil in the treatment of patients with psoriasis," Journal of the American Academy of Dermatology, vol.