Bass, "Single daily dose of methimazole compared to every 8 hours propylthiouracil
in the treatment of hyperthyroidism," Southern Medical Journal, vol.
inhibits the conversion of L-thyroxine to L-triiodothyronine.
inhibits thyroid hormone synthesis and peripheral transformation of T4 to T3 and is given orally three times a day at a dose of 0.2-0.5 mg/kg/day.
BW: body weight; VW: ventricular weight; DEO: day of eye opening; [T.sub.4]: thyroxine; [T.sub.3]: triiodothyronine; PTU: propylthiouracil
. *P<0.05, #P 0.01, +P<0.001 compared with control group (ANOvA).
Treatment with propylthiouracil
is associated with appearance of antineutrophil cytoplasmic antibodies in some patients with Graves' disease.
Both classes of antithyroid agents, Propylthiouracil
and Carbimazole, can cause liver dysfunction, which is among the small number of their idiosyncratic toxic effects.
In order to evaluate the applicability of the proposed method, the commercial medicinal sample containing 2-thiouracil from Propylthiouracil
, India, was studied.
Thiamazole (MMI) and propylthiouracil
(PTU) are antithyroid drugs (ATDs) that are used to treat GD.
He was treated with propylthiouracil
and oral prednisone 140 mg/day) for thyrotoxicosis.
Goodman, "A controlled trial of topical propylthiouracil
in the treatment of patients with psoriasis," Journal of the American Academy of Dermatology, vol.