protein kinase C


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protein kinase C

[¦prō‚tēn ¦kī‚nās ′sē]
(cell and molecular biology)
A Ca2+-dependent enzyme mediating the phosphorylation of certain cellular proteins, thereby regulating important physiological functions, such as cell growth, ion channel activity, secretion, and synaptic transmission. Abbreviated PKC.
References in periodicals archive ?
The company is applying its core expertise in the biology of specific protein kinase C (PKC) isozymes to develop highly specific activators and inhibitors of PKC isozymes for the treatment of a variety of human diseases.
Steve's extensive experience in operational and financial management, business development and commercialization strategy will be invaluable to KAI as the company rapidly advances its clinical and preclinical therapeutic pipeline of protein kinase C modulators for the acute treatment of ischemia and reperfusion injury and for diseases involving chronic regulation of angiogenesis.
Regulation of cytochrome P4501B1 (CYP1B1)in mouse embryo fibroblast (C3H10T1/2) cells by protein kinase C (PKC).
Chair of the Department of Molecular Pharmacology at Stanford University, to develop therapeutics that selectively modulate protein kinase C (PKC), a well validated pharmaceutical target.
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