Proteolysis


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proteolysis

[‚prōd·ē′äl·ə·səs]
(biochemistry)
Fragmentation of a protein molecule by addition of water to the peptide bonds.

Proteolysis

 

the hydrolysis of peptide bonds that is catalyzed by proteolytic enzymes. During proteolysis, intrinsic proteins that are undergoing the catabolic process, as well as food proteins, are split into amino acids. Proteolysis is important in the formation of enzymes, hormones, and biologically active peptides from their inactive precursors. In plants proteolysis takes part in the mobilization of the storage proteins of seeds during germination.

References in periodicals archive ?
Two-way ANOVA was used to analyze the time-dependent proteolysis in C2C12 and cardiomyocytes.
Ammonia-N in silage reflects the degree of protein degradation, and extensive proteolysis adversely affects the utilization of N by ruminants (Wilkinson, 2005).
Whereas distiller's grains combined with molasses stimulated the activity of LAB, enhanced rapid LA accumulation to cause fast drop in pH, and further inhibited the proteolysis and activity of undesirable bacteria.
Lipolysis, proteolysis and physic-chemical modifications during ripening of dry-cured duck breast.
It mainly includes the fermentation of lactose proteolysis and the degradation of fats.
Spectrophotometric Assay Using O-Phthaldialdehyde for Determination of Proteolysis in Milk and Isolated Milk Proteins.
Proteolysis in normal and pathological conditions, Kiev: Health (in Russian)
Intracellular substrate proteolysis by MMPs is involved in pathology of cardiac, neurological, protein conformational, and autoimmune diseases.
Also, among women in group 2, significant increase of the average molecular weight of peptides to two times higher than the control value was observed due to the activation of intracellular proteolysis, indicating the development of endogenous intoxication.
TIMP4 prevents ECM proteolysis in lungs [44], female genital tract, [45], eyes [46], and in transplanted tissues [47].
We investigated the folding of the proteins by limited proteolysis and found that the HDS3 mutants have altered folding patterns than wild-type GBF1.