Proteolysis


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proteolysis

[‚prōd·ē′äl·ə·səs]
(biochemistry)
Fragmentation of a protein molecule by addition of water to the peptide bonds.

Proteolysis

 

the hydrolysis of peptide bonds that is catalyzed by proteolytic enzymes. During proteolysis, intrinsic proteins that are undergoing the catabolic process, as well as food proteins, are split into amino acids. Proteolysis is important in the formation of enzymes, hormones, and biologically active peptides from their inactive precursors. In plants proteolysis takes part in the mobilization of the storage proteins of seeds during germination.

References in periodicals archive ?
An increased muscle proteolysis resulted in greater uric acid concentrations in plasma of broilers treated with dietary corticosterone (Lin et al.
Changes in physicochemical, lipolysis and proteolysis of vacuum-packed Turkish Kashar cheese during ripening.
Spectrophotometric assay using Ophthalaldehyde for determination of proteolysis in milk and isolated milk proteins.
activation of caspase activity QCR1 7/14 Aerobic Mitochondrion [up arrow] respiration, inner membrane proteolysis ERP44 13/27 Stress response, Endoplasmic [up arrow] cell redox reticulum homeostasis, lumen glycoprotein metabolic process PA2G4 16/25 Cell cycle arrest, Cytoplasm, [up arrow] cell nucleus proliferation ANXA1 7/20 Anti-apoptosis.
Cell surface localization of proteolysis of human endothelial angiotensin I-converting enzyme.
Therefore it is plausible that IMT could reverse or ameliorate inspiratory muscle proteolysis in ventilatordependent patients, by providing a net anabolic stimulus.
1-108] as a substrate in our proteolysis assay, it seems unlikely that our human kidney samples contain detectable concentrations of the processing enzyme required to yield smaller, more potent forms of BNP.
However, there are also reports revealing a decrease in serum IGFBP-3 level following 4 weeks of training, which could be caused by enhanced IGFBP-3 proteolysis in response to intensive endurance training (Schwarz et al.
The methods depend upon inhibiting invariant chain proteolysis by cathepsin S from class II MHC/invariant chain complexes, thereby reducing the competency of class II MHC molecules for binding antigenic peptides, reducing presentation of antigenic peptides by class II MHC molecules, and suppressing immune responses.
It is well-established that VHL (pVHL) regulates the protein stability of the transcription factor Hypoxia-Inducible Factor (HIF)-1 alpha through proteolysis.
Among African Americans, three distinct pathways displayed altered gene expression: cell adhesion, neutral endopeptidase, and ubiquitin-mediated proteolysis.