protoxin

protoxin

[¦prō¦täk·sən]
(biochemistry)
A chemical compound that is a precursor to a toxin.
References in periodicals archive ?
Cry1Ac protoxin is a crystal protein produced by the bacterium Bacillus thuringiensis (Bt) during sporulation.
I'-endotoxin is a globular protein molecule mount up as a protoxin and released in the gut of a pest in alkaline medium.
The chemical protoxin MPTP (1-methyl-4-phenyl-1-2-3-6- tetrahydropyridine), which produces a clinical parkinsonian syndrome, significantly lowers retinal dopamine.
Ilhuicatzi-Alvarado et al., "Cry1Ac protoxin from Bacillus thuringiensis promotes macrophage activation by upregulating CD80 and CD86 and by inducing IL-6, MCP-1 and TNF-[alpha] cytokines," International Immunopharmacology, vol.
Cry protoxin structures have been documented where a Cry 3-domain protein family with similar mode of action, including Cry1Aa, was grouped.
Cao, Adsorption Thermodynamics of Toxin (65 kDa) and Protoxin (130 kDa) from Bacillus thuringiensis by Several Minerals, Int.
Epsilon toxin is protease activated protoxin that produced mainly by C.
Purification and Protease Digestion of Protoxin. The wild type Cry1Ac and mutant toxins were purified by the method described elsewhere (Hussain et al., 2010).
The pure protoxin was eluted by a linear 0-80 per cent ethylene glycol gradient and converted to the 65 kDa mature VCC by passing through a column of bovine trypsin immobilized to Sepharose CL-4B (Sigma, USA) in 100 mM Tris-HCl buffer containing 10 mM Ca[Cl.sub.2], pH 7.8.
Endogenously occurring beta-carbolines induces parkinsonism in non-primate animals: a possible causative protoxin in idiopathic Parkinson's disease.