protoxin

protoxin

[¦prō¦täk·sən]
(biochemistry)
A chemical compound that is a precursor to a toxin.
References in periodicals archive ?
Epsilon toxin is protease activated protoxin that produced mainly by C.
This toxin is secreted as relatively inactive protoxin and is activated to a potent heat-laible toxin with the loss of an N-terminal peptide by a proteolytic enzyme produced by the organism [8].
The pure protoxin was eluted by a linear 0-80 per cent ethylene glycol gradient and converted to the 65 kDa mature VCC by passing through a column of bovine trypsin immobilized to Sepharose CL-4B (Sigma, USA) in 100 mM Tris-HCl buffer containing 10 mM Ca[Cl.
Crystal structure of the Vibrio cholerae cytolysin (VCC) protoxin and its assembly into a heptameric transmembrane pore.
METHODS: cry4, a mosquitocidal protoxin gene, was amplified by E-PCR with family and type primers that were designed from known conserved and unique regions, respectively.
thuringiensis for novel protoxin genes is to have a method that can rapidly and accurately characterize the novel subclass genes.
To test the efficiency and specificity of E-PCR with DGGE approach, we used a mosquitocidal protoxin class gene, cry4, in Bacillus thuringiensis as subject.
israelensis was used as a positive control strain, because of its well studied protoxin genes.
Bacillus thuringiensis (Bt) Cry1Ab, the protoxin sequence from Bt serovar aizawai, consists of a single 610-amino-acid polypeptide (accession no.
Bt's protoxins are harmless to people, livestock, and most beneficial insects such as bees.