For the study, seven TRD patients were administered two doses of psilocybin
, each, one week apart.
Patients were given two doses of psilocybin
a week apart.
The naturally occurring psychoactive compound psilocybin
mushrooms or 'magic mushrooms' gave the brain a 'kick start' to break out of depressive states.
Dr Robin Carhart-Harris, head of psychedelic research at Imperial College London, said: "We have shown for the first time clear changes in brain activity in depressed people treated with psilocybin
after failing to respond to conventional treatments.
In the study, reported in the journal Scientific Reports, patients with treatment-resistant depression were given a 10mg and 25mg doses of psilocybin
seven days apart.
They found that patients taking psilocybin
to treat depression showed reduced symptoms weeks after treatment.
The board approved the hallucinogen experiments - which eventually involved giving inmates LSD, psilocybin
Antidepressive, anxiolytic, and antiaddictive effects of ayahuasca, psilocybin
and lysergic add diethylamide (LSD): a systematic review of clinical trials published in the last 25 years.
Humans exhibit greater optimism and improved sense of well-being after psilocybin
Additionally, there were one arrest each for possession of psilocybin
mushrooms, LSD and cocaine, the sheriff's office said.
A small pilot trial of 12 patients with treatmentresistant depression - which in some cases had persisted for decades - found every participant experienced a reduction in symptoms a week after taking strictly controlled Class A drug psilocybin
, the psychedelic compound in magic mushrooms, may one day be an effective treatment for patients with severe depression who fail to recover using other therapies, scientists said on Tuesday.