biopsy

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biopsy

(bīäp`sē), examination of cells or tissues removed from a living organism. Excised material may be studied in order to diagnose disease or to confirm findings of normality. Preparatory techniques depend on the nature of the tissue and the kind of study intended. Incisions may be made and total or partial lesions removed in the form of wedges or cylindrical pieces, or scrapings of the surface membranes of internal organs may be collected. Needlelike instruments may be used to pierce the tissues and remove soft inner material. Once the tissue specimen has been obtained it is fixed, i.e., membrane proteins and enzymes are stabilized and chemical and histologic analyses are carried out by pathologists. Tumors are routinely biopsied in order to determine whether they are malignant. Fine needle aspiration is a technique more readily used for certain tumors or lesions because it is less expensive and damaging than traditional surgical biopsy.
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biopsy

[′bī‚äp·sē]
(pathology)
The removal and examination of tissues, cells, or fluids from the living body for the purposes of diagnosis.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.

biopsy

1. examination, esp under a microscope, of tissue from a living body to determine the cause or extent of a disease
2. the sample taken for such an examination
Collins Discovery Encyclopedia, 1st edition © HarperCollins Publishers 2005
References in periodicals archive ?
Data Source: The retrospective cohort study included 1,845 women who had a prior LEEP, prior cervical punch biopsy, or prior Pap smear.
If the pigmented lesion has crossed vermilion border, a punch biopsy is preferred aligned vertically and the margins must be painted with gentian violet to avoid misalignment while closing the defect.6
All the cases were subjected to punch biopsy except 5 cases of suspected thyroid malignancy, 12 cases of salivary gland swelling.
Punch biopsy of the skin is a simple, inexpensive, safe OPD procedure, causing minimal discomfort to the patient.
A 4-mm punch biopsy is helpful to confirm the diagnosis and is recommended in areas of early active disease, including areas that may have primary morphologic features, areas with a positive pull test (if possible), or areas that are symptomatic (if needed).
Punch biopsy revealed a perivascular and periadnexal lymphoplasmacytic infiltrate involving the superficial and deep dermis in association with irregular, papillomatous epidermal hyperplasia.
One of the masses on lateral trunk was selected, area shaved and surgically prepared, 2% Lignocaine was instilled subcutaneously all around the lesion and a punch biopsy was done using 5mm biopsy punch.
A punch biopsy sample from the right hand showed acute inflammation and suppurative granulomas of deep soft tissue.
A punch biopsy is usually done when the sample needs to include overlying skin.
These patients should have a careful examination of the vulva using a colposcope, and if a lesion is present, a 4-mm punch biopsy is warranted.