purgative


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purgative

Med
1. a drug or agent for purging the bowels
2. causing evacuation of the bowels; cathartic

Purgative

 

(also, depending on the substance used, laxative, cathartic, or aperient), a medicinal substance that increases the frequency and fluidity of stool, thus normalizing intestinal function in cases of constipation. In chemical composition, purgatives may be inorganic compounds, for example, such salts of alkali and alkaline-earth metals as sodium sulfate, Carlsbad salt artificial, and magnesium sulfate. They may also be organic compounds, for example, acids and such oils as mineral and castor oils. Some vegetation can also serve as purgatives, for example, powder of rhubarb.

The mechanism of purgative action varies. Rhubarb and phonolphthalein stimulate the chemoreceptors of the intestinal mucosa, and mineral and vegetable oils facilitate the movement of intestinal contents. Salt purgatives inhibit the absorption of water in the intestine, which increases the volume of intestinal contents and results in intensified peristalsis. The use of mineral waters as purgatives is based on the action of salts; mineral waters include the Slavianov, Morshin, Batalin, and the Izhevsk mineral waters. Closely related to salts in their action are substances that swell in water, such as linseed and sea kale.

Purgatives are used in cases of constipation and to remove poisons and poor-quality food products from the intestine (salt purgatives). The administration of purgatives is contraindi-cated in cases of intestinal inflammatory processes or pregnancy.

REFERENCE

Mashkovskii, M. D. Lekarstvennye sredstva, 7th ed., part 1. Moscow, 1972.

O. S. RADBIL

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In this study we determine the presence of phytochemicals, cytotoxicity, antioxidant and purgative effect of the fruit using Eudrilus eugenia as test subjects.
The standard oral purgative agent used in the pre-colonoscopy cleansing protocol contained sennoside A+B calcium (XM [R]; solution 250 mL, Yenisehir Lab., Ankara, Turkey).
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Hippocrates (300BC) recommended garlic for infections, wounds, cancer, leprosy, digestive disorders, pulmonary complaints, as a cleansing or purgative agent, and for abdominal growths.
Laxative used in swollen tonsillitis and chest pain Dactylorhiza hatagirea (D.Don) Soo Tubers used in backache Daphne mucronata Royle Roots purgative, bark and leaves used cutaneously Datura stramonium Linn.
Yes, the plague created opportunities for some, and yes, some economic effects were not felt until after 1375, but the immediate effect was not purgative: plague did much more than merely relieve an over-populated countryside of its excess people.
The plant was once used for purifying bad wine, and as a purgative for drunks.
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Rhubarb originated in Siberia, which is why it finds itself so at home in the British climate I guess, and was used by the Chinese for thousands of years as a purgative. The roots were also popular in medieval medicine here.