However, manifestation of ISF as primary
purpura fulminans has been described only rarely.
Varicella
purpura fulminans associated with heterozygosity for factor V Leiden and transient protein C deficiency.
Over the subsequent hospital days, the patient went into disseminated intravascular coagulopathy (DIC) and progressed to
purpura fulminans (PF).
Purpura fulminans: recognition, diagnosis andmanagement.
Purpura fulminans is the cutaneous clinical presentation of a hematological complication that includes tissue necrosis, small vessel thrombosis, and disseminated intravascular coagulation (1-2).
Schwed-Lustgarten, "Pneumococcal sepsis-induced
purpura fulminans in an asplenic adult patient without disseminated intravascular coagulation," American Journal of the Medical Sciences, vol.
Herein, we describe an infant who presented with delayed onset
purpura fulminans and was found to have autosomal recessive PCD caused by a novel homozygous PROC mutation.
Just 72 hours later the tot was diagnosed with a rare thrombotic disorder called
Purpura Fulminans and had to have both of his legs amputated.
Purpura fulminans (PF) is a life-threatening hematologic emergency in which there is skin necrosis and disseminated intravascular coagulation (DIC).
(14) Clinically, both patients manifested features of
purpura fulminans, as occurs in catastrophic APS, and presented at autopsy with signs of disseminated intravascular coagulation, but aCL or LA were not tested.
pneumoniae causes fever and
purpura fulminans mainly in children who are immunocompromised.