In the nucleus, hipercromatosis, pyknosis
, and cariolysis occur and the cytoplasm becomes homogeneously stained with eosin (Takashima & Takashi).
H&E staining showed the pathological features of acute neuron injury, such as neuronal pyknosis
, swelling, torsion, and cell body deformation.
Meanwhile, the liver showing different stages of necrosis of hepatic cells and pyknosis
(first stage of necrosis) as shown in (photo, 12).
The atresia process can be demonstrated by characteristics such as GC pyknosis
(21), dissociation of GCs from basal membrane (5), GC floatation in the antrum (22), segmentation and deformation or annihilation of oocyte nucleus (23-26).
The findings of the present study showed that MTX could induce hepatic hydropic degeneration, pyknosis
, sinusoidal dilatation and bile duct hyperplasia together with renal tubular degeneration, glomerular shrinkage and hyaline droplet precipitation.
In the present study, nicotine induced a delay in cell migration from the external granular layer to the internal layer and altered shape and pyknosis
in Purkinje cells in the cerebellum and chromatolysis of neurons in the medulla oblongata, an effect that was markedly prevented in the C.
(25) It is extremely difficult to discriminate true mitosis from mitosis mimics, including pyknosis
, apoptotic bodies, or shrunken nuclei, but such discrimination is important because, otherwise, the area is not counted as mitosis.
Figure 7A-G shows that the morphology of Saos-2 cells cultured in different extracts after 72 h incubation was normal and healthy, similar to that of the negative control, but the positive control revealed many apoptotic cells, manifested as nuclear pyknosis
It includes karyorrhexis, karyolysis, micronucleus formation, pyknosis
, binucleation, broken-egg nucleus, anucleation, etc.
Most of the nuclei of the proximal tubular cells showed degeneration including pyknosis
, karyorrhexis, and karyolysis.
The histological alterations were mainly pyknosis
, karyorrhexis, cytoplasmic vacuolation, necrosis, fatty changes and hepatocyte atrophy.
Rats receiving C[CL.sub.4] for 28 consecutive days developed a high degree of steatosis with severe cytoplasmic vacuolation and wide spread hepatocellular necrosis with nuclear pyknosis