pylephlebitis


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pylephlebitis

[¦pī·lə·flə′bīd·əs]
(medicine)
Inflammation of the portal vein.
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Another possible risk factor for the development of liver abscess after LSG is ascending migration of bacteria from the portal venous system due to pylephlebitis of the porto-mesenteric veins secondary to leak-related collection.10 However, pylephlebitis was not detected in CT images of the present case.
Pylephlebitis is defined as a septic thrombophlebitis of the portal vein and its tributaries that is associated with intra-abdominal inflammation and infections such as diverticulitis, appendicitis, cholangitis, and cholecystitis [1].
The diagnosis of pylephlebitis relies on the demonstration of portal vein thrombosis in the setting of suppurative bacteremia through aspiration of the portal vein.
PVT most commonly occurs in patients with liver cirrhosis, intraabdominal malignancy (especially hepatocellular carcinoma), intraabdominal infection (pylephlebitis and liver abscess), inherited or acquired prothrombotic disorders, MPN, or autoimmune diseases and rarely in nephrotic syndrome.
Slome, "A case of septic portal vein thrombosis (pylephlebitis)," The Medicine Forum, vol.
Yassin, "Diverticulitis complicated by pylephlebitis: a case report," Journal of Medical Case Reports, vol.
If the inflammation is not localized by the inflammatory and omental reaction, this spreads and may lead to frank pus formation, generalized peritonitis, pylephlebitis, necrosis of caecal wall or septicaemia.
Pylephlebitis, also called septic thrombophlebitis of the portal vein, is a life-threatening complication of intra-abdominal infection.
60,50,60 Table 1 Causes of Cirrhosis Alcoholic liver disease (responsible for 75% to 80% of cirrhosis cases in the United States) Long-term exposure to toxins and drugs (especially acetaminophen) Chronic viral hepatitis B, C and D Inherited metabolic diseases such as Wilson disease and hemochromatosis, both of which are marked by abnormal accumulation of copper in the liver and other organs Chronic autoimmune hepatitis and bile duct disease Chronic congestive heart failure Nonalcoholic steatohepatitis Parasitic infections (eg, schistosomiasis) Table 2 Vascular Pathologies Chronic passive congestion Cardiac cirrhosis Hepatic vein thrombosis (Budd-Chiari syndrome) (portal hypertension) Portal vein thrombosis (portal hypertension) Pylephlebitis Table 3 Fatty Liver Treatments Lose weight.
Combining MVT in the setting of bacteremia, our patient also had pylephlebitis. There are only a few case reports where inferior mesenteric vein pylephlebitis has been reported in the setting of sigmoid diverticulitis; to our knowledge this would be the first reported case of poly-microbial sepsis associated with superior mesenteric vein thrombosis related to diverticulitis [8-11].