pyridoxal phosphate

(redirected from pyridoxal)
Also found in: Dictionary, Thesaurus, Medical, Wikipedia.

pyridoxal phosphate

(pĭr'ĭdŏks`əl): see coenzymecoenzyme
, any one of a group of relatively small organic molecules required for the catalytic function of certain enzymes. A coenzyme may either be attached by covalent bonds to a particular enzyme or exist freely in solution, but in either case it participates intimately in
..... Click the link for more information.
; vitaminvitamin,
group of organic substances that are required in the diet of humans and animals for normal growth, maintenance of life, and normal reproduction. Vitamins act as catalysts; very often either the vitamins themselves are coenzymes, or they form integral parts of coenzymes.
..... Click the link for more information.
.
The Columbia Electronic Encyclopedia™ Copyright © 2013, Columbia University Press. Licensed from Columbia University Press. All rights reserved. www.cc.columbia.edu/cu/cup/

pyridoxal phosphate

[‚pir·ə′däk·səl ′fä‚sfāt]
(biochemistry)
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Low pyridoxal 5'-phosphate is associated with increased risk of coronary artery disease.
In addition to PLP, some laboratories report PA, the metabolite of pyridoxal, and the PLPto-PA ratio (2).
Abbreviations AdoMet: s-Adenosyl-L-methionine CBS: Cystathionine [beta]-synthase CBSA 409-551: Truncated cystathionine [beta]-synthase lacking the C-terminal 143 residues CBS p.P49L: Cystathionine [beta]-synthase variant harboring a proline-to-leucine substitution at residue 49 CO: Carbon monoxide CSE: Cystathionine y-lyase EDTA: Ethylenediaminetetraacetic acid [H.sub.2]S: Hydrogen sulfide KPi: Potassium phosphate MME: Monomethyl ether MST: Mercaptopyruvate sulfurtransferase NO[??]: Nitric oxide PEG: Polyethylene glycol PLP: Pyridoxal 5-phosphate r.m.s.d.: Root mean square deviation SDS-PAGE: Sodium dodecyl sulfate polyacrylamide gel electrophoresis WT: Wild type.
Toney, "Pyridoxal phosphate enzymology," Biochimica et Biophysica Acta, vol.
A novel chemical defined medium (SDM) was developed (Table 1 and Figures 3, 4, and 5), and SDM contained NaCl, L-Arg, L-Gly, L-His, L-Leu, L-Met, L-Phe, L-Thr, L-Ser, L-Cys, L-Asn, L-Glu, L-Iso, L-Lys, L-Try, pyridoxal, pantothenic acid, niacin, riboflavin, folic acid, MgS[O.sub.4]-7[H.sub.2]O, MnS[O.sub.4] x 4[H.sub.2]O, K[H.sub.2]P[O.sub.4], [K.sub.2]HP[O.sub.4], C[H.sub.3]COONa, adenine, and uracil.
Selhub, "Plasma pyridoxal 5'-phosphate concentration is correlated with functional vitamin B-6 indices in patients with rheumatoid arthritis and marginal vitamin B-6 status," Journal of Nutrition, vol.
Pyridoxal can be converted to pyridoxal phosphate, which can work as coenzyme to participate in the synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, 5-aminolevulinic acid, and so forth.
Alanine aminotransferase kit {(International Federation of Clinical Chemistry (IFCC)} without pyridoxal phosphate activation.
Relationship between pyridoxal 5'- phosphate deficiency and aminotransferase levels in alcoholic hepatitis.
Each subunit tightly attaches to one molecule of pyridoxal 5'-phosphate.