Other evidence for HP[O.sub.4.sup.2-] ion derives from the formation of pyrophosphate
on heating at 400-600[degrees]C (13) by the reaction
In the prebiotic atmosphere, inorganic pyrophosphates
formed by photo-phosphorylating reactions and enrichment of enantiopure molecular conformations provides a thermodynamical driving force for the evolution of biogenetic process.
I think the Michaelis complex for the capping reactions are phosphates sandwiched between calciums, derived from the site for the original leaving group, pyrophosphate
. All of the capping reactions are present because such a complex is there to capture this transition state, which was selected for hydrolysis.
A significant amount of time during the meeting focused on detailing the proper method of preparing the methylene blue and tetrasodium pyrophosphate
In elderly patients, calcium pyrophosphate
dehydrate is a common finding in many fibrocartilages and hyaline articular cartilages of larger joints, tendons, and soft tissues.
In CPPD, ultrasound was useful in identifying calcium pyrophosphate
crystals via specific anatomic characteristics of the crystals and provided a radiation-free alternative to the conventional X-ray.
Additional keywords: dithionite, organic complexes, oxalate, oxides, pyrophosphate
, soil classification.
Like gout, pseudogout is characterized by crystal-like deposits that settle in the joints and cause pain and warmth/redness, but these deposits are composed of a different substance: calcium pyrophosphate
The main difference between the two is that in pseudogout the crystals are formed from calcium pyrophosphate
dihydrate (CPPD), while gout stems from uric acid crystals.
In pre-clinical studies, the experimental therapy has shown potential to generate plasma pyrophosphate
and to restore it to appropriate physiological levels, thereby preventing calcification in the vasculature and kidneys and normalizing bone.