pyruvate

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Related to Pyruvate carboxylase: gluconeogenesis

pyruvate

[pī′rü‚vāt]
(biochemistry)
Salt of pyruvic acid, such as sodium pyruvate, NaOOCCOCH3.
References in periodicals archive ?
[28.] Adina-Zada A, Zeczycki TN, Attwood PV Regulation of the structure and activity of pyruvate carboxylase by acetyl CoA.
* Elevated L/P ratio (>20) can indicate respiratory chain disorders, Krebs cycle disorders and pyruvate carboxylase deficiency.
However, recent studies ensure that the activity of pyruvate carboxylase is prominent over PEP carboxylase (PetersWendisch, et al., 1997).
Biotin is also essential for the function of pyruvate carboxylase, which plays a role in the conversion of pyruvate to oxaloacetate.
In this group, a biochemical defect was documented in 21 patients: complex IV deficiency, n = 8; complex I deficiency, n = 5; complex II+III deficiency, n = 2; multiple complexes deficiency, n = 5; pyruvate carboxylase deficiency (type B), n = 1.