pyruvate

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pyruvate

[pī′rü‚vāt]
(biochemistry)
Salt of pyruvic acid, such as sodium pyruvate, NaOOCCOCH3.
References in periodicals archive ?
Parameters assayed were thiobarbituric acid reactive substance (TBARS), serum glutamate oxaloacetate transaminase (SGOT), serum glutamate pyruvate transaminase (SGPT), reduced glutathione (GSH), ascorbic acid, tocopherol, super oxide dismutase and glutathione peroxidase in red blood cells (RBC) and in liver.
Morphine administration resulted in elevated serum glutamate oxaloacete transaminase and serum glutamate pyruvate transaminase activities.
Serum oxalacetate and pyruvate transaminase activity (SGOT & SGPT) was determined by the method of Reitman and Frankel (1957).
Serum albumin was 28 g/L (normal 33-48 g/L), serum glutamic oxaloacetic transaminase 54 U/L (normal 5-40 U/L), serum glutamic pyruvate transaminase 58 U/L (normal 5-40 U/L), and erythrocyte sedimentation rate 74 mm/h.
The pyruvate is converted to glutamate by serum glutamate pyruvate transaminase.
Biochemical parameters, such as serum glutamic oxaloacetate transaminase, serum glutamic pyruvate transaminase (Reitman and Frankel, 1975), alkaline phosphate (Kind and King, 1972), total bilirubin, direct bilirubin (Mally and Evelyn, 1937) and liver glutathione (Ellman, 1959), were analyzed according to the standard method.
After controlling for other covariates, the multivariate logistic regression analysis showed that the significant factors related to fatty liver were male sex, obesity, hyperglycemia, hypertriglyceridemia, elevated glutamate pyruvate transaminase level, and hyperuricemia, Elevated glutamate oxaloacetate transaminase level was negatively associated with fatty liver.
Elevated liver enzymes (glutamate oxalacetic transaminase 155 U/L, glutamate pyruvate transaminase 379 U/L) were found, along with elevated lactate dehydrogenase 911 U/L (normal 130-290 U/L) and C-reactive protein 4.