quellung reaction

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quellung reaction

[′kwel·əŋ rē‚ak·shən]
(microbiology)
Swelling of the capsule of a bacterial cell, caused by contact with serum containing antibodies capable of reacting with polysaccharide material in the capsule; applicable to Pneumococcus, Klebsiella, and Hemophilus.
References in periodicals archive ?
For each strain transferred to our laboratory, we promptly identified capsular type by quellung reaction, and resistance genotype was determined by real-time PCR.
Results were confirmed by the Quellung reaction with newly available antiserum to identify 6C serotype (Statens Serum Institute, Copenhagen, Denmark).
Serotype 6C was identified in 2007 on the basis of its distinct binding patterns with 2 monoclonal antibodies; serotype 6C had previously been typed as 6A according to the standard quellung reaction.
Isolates were serotyped by using the Quellung reaction (9).
pneumoniae by standard methods, and serotypes were determined by the Quellung reaction.
Conventional serotyping using the Quellung method was performed where possible; culture-negative or incompletely genotyped PFs were serotyped by using a real-time PCR that targets different capsular locus genes (13).