quellung reaction


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quellung reaction

[′kwel·əŋ rē‚ak·shən]
(microbiology)
Swelling of the capsule of a bacterial cell, caused by contact with serum containing antibodies capable of reacting with polysaccharide material in the capsule; applicable to Pneumococcus, Klebsiella, and Hemophilus.
References in periodicals archive ?
Serotyping based on the Quellung reaction requires expensive reagents and substantial training and experience to perform reliably.
Serotyping was performed by using the quellung reaction with antiserum for serogroup 6, factor 6b, and factor 6c (Statens Serum Institute, Copenhagen, Denmark).
In 51 of these, a pneumococcal serotype could be identified via the conventional Quellung reaction. Evidence of pneumococcal infection in 99 (84%) of 118 culture-negative PF samples was found on the basis of ply or wzg gene detection.
Serotyping, performed by Quellung reaction, showed a 35F serotype.
All pneumococcal isolates were serotyped according to standard methods by using the Quellung reaction (15-17).
Serotyping was conducted by using the quellung reaction with reagents from Statens Serum Institut (Copenhagen, Denmark) (18).