Quinacrine shows a 100% clearance rate in refractory giardiasis after treatment with metronidazole, tinidazole, and nitromidazole has failed.
Quinacrine does come with a major concern of its own: the risk of aplastic anemia.
The interaction of
quinacrine with adenine nucleotides.
Quinacrine (Atabrine) in the treatment of neoplastic effusions.
Malaria disappeared after 3-5 years without additional measures beyond occasional
quinacrine use in areas where An.
These drugs could be divided into two main types: acridines, which include mepacrine (
quinacrine), used since 1930, and quinoleines, which include chloroquine (amodiaquine), proguanil, chlorproguanil, pyrimethamine, primaquine, quinocide, pamaquine.
According to the companies, Curaxins include CBL0137, which is a carbazole, and CBL0102, which is a
quinacrine.
Severe starvation medium was supplemented with protease inhibitors, 1mM phenylmethylsulfonyl fluoride, 10 [micro]g [mL.sup.-1] leupeptin, 100 [micro]M E64-d, and 10 mM
quinacrine. The medium was adjusted to pH 7.0 by adding KOH.
The "protector" effect has also been reported with respect to the aromatic mutagen
quinacrine, ICR-191, ICR-170, IQ-type heterocyclic aromatic amines, and neocarzinostatin in the presence of caffeine and its derivatives [44-47].
[14] verified the effect of various anti-inflammatory agents as retinoic acid,
quinacrine and dipyridamole in reducing adhesions in animals.
When
quinacrine was added to the treatment regimen of the nonresponders, two-thirds experienced a lessening of their disease.