racemate


Also found in: Dictionary, Medical, Wikipedia.

racemate

[′ras·ə‚māt]
(organic chemistry)
An equimolar mixture of the two enantiomers (+ and -, or R and S) of a substance; it is optically inactive.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
R (+) amlodipine is involved in local NO formation through the kinin pathway and this may lead to loss of the precapillary reflex vasoconstriction and development of edema when racemate mixture is used.
But the practice of first patenting a racemate and then separately patenting an enantiomer years later is problematic.
While a somewhat unusual case, the SCC confirmed that the selection of one enantiomer from a known racemate, with the disclosure that the selected enantiomer had better activity, constituted a valid selection.
version of the racemate drug is also not considered to be as new
Anticonvulsant activity of the linalool enantiomers and racemate: investigation of chiral influence.
As a kind of chiral pollutant, the interference with endocrine system of DEHP is enantioselective, it is of great significance in separating the toxic racemate of DEHP with MIPs as the stationary phase, but few researches have focused their attention on the preparation of MIPs for DEHP.
Commercially, the drug is available as a racemate mixture with equal 'levo' and 'dextro' isomers.
Consequently considerable effort is being made to obtain optically pure profens through asymmetric chemical synthesis, catalytic kinetic resolution [105], resolution of racemate via crystallization, and chiral chromatographic separations.
The XRD pattern corresponds to that of PZQ racemate crystal, as reported in literatures [44].
Central Drug Research Institute (CDRI) developed a promising antimalarial compound, 97/63 (Racemate) (Figure 1(a)), in its drug discovery program.
However, studies have also shown in a model of cerebroischemic stroke that while two enantiomers of a lipophilic [beta]2AR-agonist provide neuroprotection by activating astrocytes and inducing production of neurotropic factors, one racemate might also induce more adverse side-effects [23, 24].