Osteomalacia

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Related to rachitic: rachitis, rickets, rachitic pelvis

osteomalacia

[¦äs·tē·ō·mə′lā·shə]
(medicine)
Failure of bone to ossify due to a reduced amount of available calcium. Also known as adult rickets.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Osteomalacia

 

a bone disease that is manifested by softening and deformity of bone as a result of disturbances in mineral metabolism; usually, the depletion of calcium salts, phosphoric acid, and vitamin D is the cause. Osteomalacia generally occurs in women, especially during pregnancy, in which case the pelvic bones and adjacent portions of the skeleton are particularly affected. Recovery occurs in the postpartum period. Bones may remain permanently deformed after osteomalacia as a result of calcification.

REFERENCE

“Osteomaliatsiia.” In Bol’shaia meditsinskaia entsiklopediia, 2nd ed., vol. 22, Moscow, 1961.
In animals. Osteomalacia in animals is manifested clinically by a decreased and unusual appetite, during which the animal exhibits pica and eats inedible objects. Other symptoms are emaciation and lowered productivity, lameness, loose teeth, sluggishness, curvature or sagging of the spinal column, and bone fractures. The diagnosis is based on analysis of the mineral and vitamin D content of feed; the calcium, phosphorus, and phosphatase content of blood; and roentgenograms of the tail vertebrae. Osteomalacia in animals is prevented by exercise, by regular checks of the feed and inclusion of optimum quantities of minerals and vitamins, and by ultraviolet irradiation while the animals are in their stalls.

REFERENCE

Vnutrennie nezaraznye bolezni zhivotnykh. Edited by A. M. Kolesov. Leningrad, 1972.
The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Moreover, in this study it is the rachitic individuals with lower [delta][.sup.15]N values, and it is very unlikely they were growing faster than non-rachitic individuals given the detrimental effect of rickets on growth.
More than one clinical signs like rachitic rosary and widening of wrist joints were found in 65% patients; both serum calcium and phosphate were low in 32% cases.
The first observed findings in bone and joints include deformities such as craniotabes, metaphyseal enlargement, prominence of costochondral joints (rachitic rosary), delayed closure of the anterior fontanel, Harrison's grooves and thoracic anomalies (1,26).
A repeat physical exam and X-rays failed to show any craniotabes, widened sutures, rachitic rosary, or enlarged wrists.
Chest examination revealed prominent rib cage with rachitic rosary.
Hafner's nephew, the sixteen-year-old Roman, whose bones lie below the skeleton of his rachitic uncle in the clay vessel in which the pandapigl was rendered, from the bones of slaughtered animals, to be brushed on the horses around the eyes, nostrils, and belly to protect them from mosquitoes and horseflies, began the cycle of suicides in the village of Maximilian's birth.
She stared at me, did not seem aware of the Rachitic lame jackass that stood before the ancient Painted cart, awaiting the grunt to pull, Urinating on the stone where she stood, a stream Of warm wet staining her dirt-worn feet, Incensing the close, stench-laden heat of the moment, A moment forever burnt into the sear of my eyes.
Patients with HVDRR develop symptoms related to growth retardation and rachitic skeletal deformities including smooth bowing of the legs, gait disturbance, knock knees, metaphyseal widening, frontal bossing, and horizontal depression along the lower border of the chest [Farach-Carson and Nemere, 2003].
lt is possible they are confusing the study with another of ours where we did in fact report on the presence of rachitic like lesions in children living in another part of South Africa where endemic fluorosis was evident and water fluoride concentrations ranged from 8-12 ppm (4).
The assay was a radioreceptor-based procedure that required the raising of rachitic chicks as a source of the labile vitamin D receptor (VDR), which was isolated from them on a routine basis.
If left untreated, this disease can result in fractures, rachitic changes, and shorter stature later in life, he said.
Secondary hyperparathyroidism from inadequate calcium absorption in the gut is the underlying pathophysiology for the rachitic changes in HVDRR.