Melatonin As An Antioxidant & Free Radical Scavenger
 This assay is based on the principle of reduction of the absorbance of ethanol solution of DPPH by a free radical scavenger
. Reagents required for this assay were DPPH and ethanol.
Melatonin eliminates H2O2 by increasing the activity of enzymes and yields a product N-acetyle-N (2) formyl-5-methoxy-kynuramine which donates two electrons and acts as free radical scavenger
. It also neutralizes the most dangerous endogenous reactive species i.e.
Quercetin (QT), a strong antioxidant and free radical scavenger
and a natural flavonoid, has a wide range of biological and therapeutic effects.
Whereas, compound 3 (IC50 = 149.6 +- 1.7 uM) was moderate radical scavenger
. Only two compounds of the series 15 and 11 have shown less than 50% inhibition and were not evaluated for their IC50 values.
Curcumin, one of the active components of Curcuma longa, has been demonstrated to exert a number of actions, including as an antioxidant as a free radical scavenger
and in suppressing inflammatory reactions.
Nevertheless, several of these essential oils have also antimicrobial and antioxidant activities, which makes then very important for other uses, like the alpha-tocopherol or Vitamin E, a classical lipophilic antioxidant well known by its free radical scavenger
properties [17, 18].
The results of the present study indicate that the novel free radical scavenger
edaravone may act as a renoprotective agent against chronic nephropathy induced by CsA by its antioxidant property and possibly through inhibiting iNOS gene expression.
Gulpn showed that resveratrol is an effective DPPH radical scavenger
Modulation of Mitochondrial Parameters by Radical Scavenger
Here, we tried to evaluate whether 3-methyl-1-phenyl-2-pyrazolin-5-one (MCI-186), a free radical scavenger
, might influence BMSCs migration to ischemic brain, which could promote neurogenesis and thereby enhance treatment effects after stroke.
Manganese is a co-factor for the enzyme superoxide dismutase, which is a very powerful free radical scavenger
. Potassium is an important component of cell and body fluids that helps controlling heart rate and blood pressure.