Photomicrograph of spleen of (a) control animal showing normal histological structures, (b) CCl4 treated animal had hyperplasia of lymphoid follicle with rarefication
of lymphoid elements, (c) CCl4 treated animal showing eosinophilic edematous changes, and (d) CCl4-kefir treated mouse had more or less normal histological structures
Over the years these mechanisms impair renal function by vascular rarefication
, interstitial fibrosis, and nephron degeneration.
No new species occur in the south, it is just a rarefication
Even though the exact origin of such business environments is unclear, many authors agree that recent phenomenon such as globalization, technology dissemination, regulation, disintegration and demand rarefication
could be one of the causes of such accelerated disruptive and unstable business environments.