recognition sequence


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recognition sequence

[‚rek·ig′nish·ən ‚sē·kwəns]
(cell and molecular biology)
A specific sequence of nucleotides at which a restriction endonuclease cleaves a deoxyribonucleic acid molecule.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
The sequence logos for the recognition sequences of the four TFs are from the JASPAR database [15].
If the miRNA recognition sequence binds to miRNA expressed in the desired cells, the expression of the regulatory protein is suppressed, thus distinguishing the cell type from others that do not contain the miRNA and express the protein.
Enterokinase possesses trypsin-like activity and specifically cleaves after lysine residue at a canonical recognition sequence (DDDDKX) [55].
Two restriction enzyme recognition sequences, BglII and Kpn I, were added to the N terminal and C terminal of the fusion protein, respectively.
Furthermore, they derived novel recognition sequence patterns for N-glycosylation.These findings constitute an important progress in proteomics, because they help to understand the processes inside of the human body even better.
The reagent comprises a surface to which is linked an enzyme donor fragment through a protease recognition sequence, where the enzyme donor fragment complexes with an enzyme acceptor fragment to form an active indicator enzyme when the enzyme donor fragment is cleaved from said surface.
The Dral assay is based on Whittaker and Southern's [41] finding that restriction enzyme activity can be inhibited by the presence of DNA damage at the recognition sequence. Since any alteration of the bases within this recognition sequence would be expected to inhibit cleavage, UV irradiation of substrate DNA should destroy potential cleavage sites.
The smaller the recognition sequence, the smaller the average size of the fragments produced and thus the greater the number of different fragments generated by the digestion.