recognition site


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recognition site

[‚rek·ig′nish·ən ‚sīt]
(cell and molecular biology)
The nucleotide sequence in duplex deoxyribonucleic acid (DNA) to which a restriction endonuclease binds initially and within which the endonuclease cuts the DNA.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
In order to elucidate this matter, we constructed a variant of Sema3C carrying point mutation (R745A) at the basic domain at the hypothetical furin recognition site [sub.742][RNRR.sub.745], which would render Sem3C uncleavable at this particular location.
The LIG_CYCLIN_1 motifs in lined with amino acid residues amino acid residues RDLKV (323-327), which is a substrate recognition site that act together with cyclin and increases phosphorylation of cyclin/cdk complexes.
The designed forward and reverse primers were as follows: forward primer introduced Hind III recognition site underlined 5'-CAA TTA AA GCT TAT ATG CAT CAC CAT CAC CAT CAC ATG TCC TGC GGT AAC GCC AAG-3', and reverse primer introduced EcoRI recognition site underlined 5'-CAT GGA ATT CTT ACT GCT TGC TGA AGT ATCC-3'.
Spike glycoprotein cleavage recognition site analysis of infectious bronchitis virus.
One hypothesis proposed for the lac repressor system is that the lac repressor slides on one-dimensional DNA to find the recognition site, and this hypothesis is supported by image analysis in living cells [16].
The number and modality of the recognition sites is very dependable in respect of molar relation between template molecule and functional monomer.
It happens because the chosen restriction enzyme (Bg/I) has two separated recognition sites (Fig.
The issues that remain to be determined include (a) where the proBNP processing occurs after secretion, (b) what protease works as a convertase for the secreted proBNP, (c) how the BNP convertase can access the recognition site in proBNP that is likely masked by glycosylation, and (d) whether CHF patients have any defect in the processing steps of secreted proBNP.
FJ88355761), and more particularly those detectable on agarose gels but showing negative signal with PARV4-O TaqMan assay because of mismatches identified on the probe recognition site (Figure).
The linker sequence contains a cleavage recognition site for a disease specific protease such as a cancer, fungal, viral or parasitic protease.