redifferentiation


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redifferentiation

[rē‚dif·ə‚ren·chē′ā·shən]
(physiology)
The return to a position of greater specialization in actual and potential functions, or the developing of new characteristics.
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Keywords Cell redifferentiation * Eriophyidae galls * Insect galls * Nematode galls * Nutritive tissue * Plant anatomy
Since transplantation of liver tissue or pancreatic islets is hampered by the shortage of donor tissues [5] and the lack of methodology to maintain primary hepatocytes and pancreatic [beta] cells in a differentiated state in long-term in vitro culture [6], PBMCs may represent, after their tissue-specific redifferentiation, a virtually unlimited source of cells for autologous transplantation.
Remedi, "Pancreatic [beta] cell dedifferentiation in diabetes and redifferentiation following insulin therapy," Cell Metabolism, vol.
Redifferentiation therapy of differentiated thyroid carcinoma with retinoic acid: basics and first clinical results.
More recently, a published study showed that, during limb regeneration, muscles were regenerated by completely different mechanisms in these two salamander species: (1) dedifferentiation, proliferation, and redifferentiation in newts and (2) satellite cells in axolotls [19, 33, 34].
A deteriorated adipogenic differentiation program or redifferentiation into more premature adipocytes (fibroblasts) could possibly be caused by systemic inflammation.
Zheng, "Redifferentiation of human hepatoma cells induced by synthesized coumarin," Cell Biology International, vol.
In fact, Cd is one of the most potent agents known to induce transdifferentiation, that is, metaplasia of the pancreatic cells [44, 45], and since the process of metaplasia involves cellular dedifferentiation, proliferation, and redifferentiation, it may increase the risk for neoplasia [46].
Plasticity of rat bone marrow-derived 5-hydroxytryptamine-sensitive neurons: dedifferentiation and redifferentiation. Cell Biol.
The organogenic events occur by cellular differentiation, dedifferentiation and redifferentiation, depending on the resumption of the meristematic activity in the mature cells (MENDONCA et al., 2012) from the adjacent tissue.
For example, in a severe combined immunodeficiency (SCID-Hu) mouse model for prostate cancer bone metastasis, maspin expression in prostate cancer induced tumor cell redifferentiation and blocked tumor-induced bone remodeling [22].