regulon


Also found in: Medical, Wikipedia.

regulon

[′reg·yə‚län]
(genetics)
In bacteria, a system of genes, formed by one or more operons, which regulate enzyme induction and whose activity is controlled by a single repressor substance.
References in periodicals archive ?
The chloride regulon of Halobacillus halophilus: a novel regulatory network for salt perception and signal transduction in bacteria.
These pseudogenes were involved in carbohydrate transport (ptsA) (14-bp deletion), lipopolysaccharide (LPS) biosynthesis (waal) (16-bp insertion), and protein synthesis (tufB) (790-bp deletion, total gene deletion); we identified no pseudogene among the genes of the flagellar regulon. The pseudogene involved in carbohydrate transport, ptsA, controls the import of carbohydrates, such as mannose, fructose, and N-acetyl-glucosamine (9), 3 carbohydrates used by Str.2011 but not Str.2014 or Str.2015.
Fookes et al., "Elucidation of the RamA Regulon in Klebsiella pneumoniae Reveals a Role in LPS Regulation," PLoS Pathogens, vol.
Schneiders, "Elucidating the regulon of multidrug resistance regulator RarA in Klebsiella pneumoniae," Antimicrobial Agents and Chemotherapy, vol.
McCoy et al., "A miR-19 regulon that controls NF-[kappa]B signaling," Nucleic Acids Research, vol.
(6,7) The plant molecules acetosyringone and a-hydroxyacetosyringone induce the expression of the entire vir regulon in Rhizobium as well as the formation of T-DNA intermediate molecules.
The mechanisms of such cytokine mediated modulation of hspX expression are yet to be fully explored, which may be mediated through dormancy regulon dosR.
Such a system in which multiple genes expression are regulated is termed as phasevarion (phase variable regulon).
Some of these virulence genes include the outer membrane protein (ompW) gene, toxR regulon, Zonula occludens toxin (zot) gene, pore-forming toxin haemolysin (hlyA), and the heat-stable enterotoxin (stn/sto) gene.
Liu et al., "Nucleotide composition of cellular internal ribosome entry sites defines dependence on NF45 and predicts a posttranscriptional mitotic regulon," Molecular and Cellular Biology, vol.