Relaxants

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Relaxants

 

substances that decrease the tonus of skeletal musculature, which is manifested by a decrease in motor activity to the point of complete immobility.

Depending on the way in which they act, relaxants are classified as curariform agents, which block transmission of excitation through the neuromuscular synapse, that is, from the motor nerves to the muscle (such relaxants are used in anesthesiology for the complete relaxation of musculature), and centrally acting substances, which influence the central nervous formations that participate in the regulation of muscle tonus. Centrally acting relaxants, such as Meprotan and Mydocalm, are used in neurological practice to treat cerebrospinal and cerebral spastic paralysis, parkinsonism, and other disorders.

References in periodicals archive ?
Mori was arrested Saturday on suspicion of attempting to kill the girl by intravenously administering her with dangerous levels of muscle relaxant at Hokuryo Clinic.
The use of rocuronium and then sugammadex in Alzheimer's patients on donepezil who need relaxant anaesthesia would seem an ideal solution.
s (Frazer PA) Amrix, which is a once-a-day muscle relaxant, was launched last year," Sanderson said.
Sugammadex works in an entirely novel way to encapsulate the muscle relaxant molecule and restore muscle function so that patients can quickly breathe on their own again.
The judge rejected claims by Suda's defense counsel that the patient was close to death and that his death was not due to the injection of muscle relaxant, citing test results.
During Mrs Aru's eight-day trial, the court heard that instead of administering a sedative, she picked up a syringe containing the muscle relaxant Vecuronium and injected him.
Since flavonoids have been described to possess relaxant properties (Laekeman et al.
The court heard the muscle relaxant was in a syringe alongside the sedative.
Police believe her attacker used zimovane - a muscle relaxant - to drug her.
Charles Mummery, who gave him prescriptions for all kinds of drugs that could leave you too drowsy to do the dishes, let alone fly a plane: the sedatives Valium and Dalmane, and the muscle relaxant Anaprox.
In addition, the muscle relaxant dantrolene and several medications that increase the transmission of the neurochemical dopamine in the brain (believed to be impeded by neuroleptics) have recently been shown to ease NMS.