Relaxants

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The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Relaxants

 

substances that decrease the tonus of skeletal musculature, which is manifested by a decrease in motor activity to the point of complete immobility.

Depending on the way in which they act, relaxants are classified as curariform agents, which block transmission of excitation through the neuromuscular synapse, that is, from the motor nerves to the muscle (such relaxants are used in anesthesiology for the complete relaxation of musculature), and centrally acting substances, which influence the central nervous formations that participate in the regulation of muscle tonus. Centrally acting relaxants, such as Meprotan and Mydocalm, are used in neurological practice to treat cerebrospinal and cerebral spastic paralysis, parkinsonism, and other disorders.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
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