replicon


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replicon

[′rep·lə‚kän]
(genetics)
Each deoxyribonucleic segment that acts as a unit of replication.
References in periodicals archive ?
Curry et al., "The combination of grazoprevir, a hepatitis C virus (HCV) NS3/4A protease inhibitor, and elbasvir, an HCV NS5A inhibitor, demonstrates a high genetic barrier to resistance in HCV genotype 1a replicons," Antimicrobial Agents and Chemotherapy, vol.
In this study, just IncFI[I.sub.Y] plasmid replicon were detected mostly in strains of the pathogenic biotype 4 isolated from human diarrheic feces; however, it did not relate to any acquired resistance genes (Table 1).
Quantitative Proteomics Analysis of the Hepatitis C Virus Replicon High-Permissive and Low-Permissive Cell Lines.
Development of porcine respiratory and reproductive syndrome virus replicon vector for Foot-and-mouth disease vaccine.
The plasmid encoding OXA-48 [beta]-lactamase did not belong to any known PCR-based replicon typing.
These are constructed based on the OH replicon [5] and pBBori7, which was created using oriC/orc7 from Halobacterium sp.
Both wild-type (WT) and codon-optimized (OP) PI239 were cloned into a geminivirus-derived single DNA replicon system.
Bar-Ilan et al., "Dengue virus replicon expressing the nonstructural proteins suffices to enhance membrane expression of HLA class I and inhibit lysis by human NK cells," Journal of Virology, vol.
Currently, HCV sub- or full-length genomic replicon or infected cells were commonly used to analyze drug-resistance profile of DAA [17], and there are several methods to evaluate the emerged drug-resistance [17].
Long stretches of short tandem repeats are present in the largest replicons of the Archaea Haloferax mediterranei and Haloferax volcanii and could be involved in replicon partitioning.