restriction point


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restriction point

[ri′strik·shən ‚pȯint]
(cell and molecular biology)
In the mammalian cell cycle, a time late in the G1 phase at which the cell commits to the replication of its deoxyribonucleic acid (DNA).
References in periodicals archive ?
The compound we identified forces the catastrophic failure of the normal virus amplification cycle and illustrates a new drug-accessible restriction point for poxviruses in general," said John Connor, PhD, assistant professor of microbiology at BUSM.
It is far easier to create a spot restriction in the sprue and carefully monitor pouring time to detect erosion of this restriction point.