Reticulin


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reticulin

[rə′tik·yə·lən]
(biochemistry)
A protein isolated from reticular fibers.

Reticulin

 

(1) An insoluble fibrillar protein found in reticular tissue fibers in man and animals. The term has a morphological meaning in that the fibrils of these fibers consist of protein from the collagen group, while glycoproteins form the fibers’ amorphous part.

(2) An antibiotic (synonym hydroxystreptomycin) produced by the actinomycetes Streptomyces griseo-carneus and S. reticuli. It is similar in chemical structure and biological action to streptomycin.

(3) An alkaloid isolated from the tropical plant Annona reticulata.

References in periodicals archive ?
Data noted age at presentation, gender, medical history, physical examination, blood and bone marrow investigations such as, haemoglobin levels, blood cell count myeloperoxidase activity, periodic acid-Schiff and reticulin staining as well as final diagnosis.
Focal and Diffuse fibrosis was seen in 20 (87%) cases, ranging from grade I to III by reticulin staining and unremarkable in 3 (13%) cases.
September 2016: Bone marrow biopsy comments: Chronic lymphocytic leukemia (10% involvement); JAK2 mutation positive, marked reticulin fibrosis, consistent with myeloproliferative neoplasm, such as primary myelofibrosis.
In addition to reticulin stain, a number of immunomarkers have been shown to be of value in aiding in the distinction (Table 5).
On the same occasion, liver tissue samples were also taken, fixed with 10% formaldehyde, stained using hematoxylin and eosin (HE), periodic acid-Schiff and reticulin stain protocols and analyzed with light microscopy.
Myxoma is defined as "a tumor composed of sometimes spindle-shaped cells set in a myxoid stroma containing mucopolysaccharide, through which course very delicate reticulin fibers in various directions and which is locally invasive.
13) Grade 1 Loose connective tissue, cell-rich, old and new fibrin, fine reticulin fibers 2 Connective tissue with cells and capillaries, few collagen fibers 3 Connective tissue more firm, fewer cells, more vessels, few elastic and smooth muscle fibers 4 Old firm granulation tissue, cell-poor, serosal layers hardly distinguishable TABLE 3.
Histologically, PXA has lipidized pleomorphic giant cells, fascicles of spindled cells in a reticulin rich stroma, eosinophilic granular bodies (EGBs) and a lymphocytic infiltrate.
Hematoxylin and eosin stained sections were examined and few special stains such as PAS and reticulin were performed wherever required.
Reticulin Stain Solution Kit Histopathology (Ready to use)