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An increase in the number of histiocytes, monocytes, or other reticuloendothelial elements.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



a term used until the mid-1970’s to designate any one of various tumors of the blood system and some types of leukemia and hereditary disease involving the accumulation of lipids. The use of the term was based on the hypothesis that hematopoietic cells originate from reticular-tissue cells; it was also based on a certain morphological resemblance between tumor cells and normal reticular cells. Since it has been established that the formed elements of the blood originate from a mobile lymphocyte-like stem cell while the cells of bone-marrow stroma have their own precursors, the term “hemoblastosis” is now used in the medical literature to designate various types of tumors of hematopoietic tissue. The term “reticulosis” now refers only to tumors originating from cells of bone-marrow stroma and of the lymphatic system. Thus, reticuloses do not include leukoses, since reticular cells are not hematopoietic. Reticuloses also do not include reactive proliferations of reticular cells in tuberculosis, sepsis, infectious mononucleosis, and collagen diseases because these processes do not have the characteristics of malignant growth.


Novoe v gematologii. Edited by A. I. Vorob’ev and lu. I. Lorie. Moscow, 1974.
The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Multicentric reticulohistiocytosis with arthritis and cardiac infiltration: regression following treatment for underlying malignancy.
Congenital self-healing reticulohistiocytosis (Hashimoto-Pritzker disease): ten-year experience at Dallas Children's Medical Center.
Multicentric reticulohistiocytosis is a multi- system disorder which mainly involves the skin, joints and mucous membrane.
Histopathology helps to differentiate multicentric reticulohistiocytosis from eruptive xanthogranuloma and juvenile xanthogranulomas.
With the help of clinical findings, histopathological and immunocytochemical studies we confirmed the diagnosis of ulcerative multicentric reticulohistiocytosis. In the literature very few such cases have been reported.
Multicentric reticulohistiocytosis: a proliferation of macrophages with tropism for skin and joints, part II.
Multicentric reticulohistiocytosis associated with ovarian cancer.
Multicentric reticulohistiocytosis: systemic macrophage disorder.
Multicentric reticulohistiocytosis masquerading as lepromatous leprosy.
Immunohistochemical profile of multicentric reticulohistiocytosis [review].