This report documents the most complex case of porcine congenital microphthalmic syndrome to the authors' knowledge, characterized by microphthalmia, multiple persistent pupillary membranes (PPMs) which consisted of both iris-to-iris and iris-to-lens, microphakia with cataract formation, myovascularised membrane in the vitreous, retinal detachment, and retinal dysplasia
Large occipital encephaloceles have been found associated with optical, choroidal and retinal dysplasia
; severe ocular alterations; central nervous system anomalies; epilepsy; dermoid cyst; tectocerebellar dysraphia and necrosis.
[1,8] Significant ocular pathology (microphthalmia, colobomas, retinal dysplasia
and cataracts) occurs in up to 50% of patients, and sensorineural hearing loss has been reported.