rheumatoid arthritis


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rheumatoid arthritis

a chronic disease of the musculoskeletal system, characterized by inflammation and swelling of joints (esp joints in the hands, wrists, knees, and feet), muscle weakness, and fatigue

rheumatoid arthritis

[′rü·mə‚tȯid är′thrīd·əs]
(medicine)
A chronic systemic inflammatory disease of connective tissue in which symptoms and changes predominate in articular and related structures. Also known as atrophic arthritis; chronic infectious arthritis; proliferative arthritis.
References in periodicals archive ?
Chapter 1 provides an introduction to the report, whilst chapter 2 provides an overview of the trends in rheumatoid arthritis partnering since 2010, including a summary of deals by industry sector, stage of development, deal type, and technology type.
Coverage of Route of Synthesis of Active Pharmaceutical Ingredient associated with Rheumatoid Arthritis drugs.
Seventy-five percent of stool samples from patients newly diagnosed with rheumatoid arthritis carried P.
In 2003, a new class of medicine, referred to as biologic disease-modifying anti-rheumatic drugs (bDMARDs), became available for treatment of rheumatoid arthritis in Australia, broadening the treatment options.
The analysis also showed that patients with rheumatoid arthritis who were treated with a statin had a 57% statistically significant reduced risk of dying, compared with rheumatoid arthritis patients not treated with a statin.
They examined 18 SNPs in 830 Japanese people with rheumatoid arthritis and 658 people without the disease.
We were able to show that the combination of smoking and lack of the GSTM1 gene was correlated with a greater likelihood to be rheumatoid factor positive, and the questionnaires and radiology studies confirmed that these same individuals have more advanced, more severe rheumatoid arthritis," Mattey says.
TNF is a protein of the body's immune system that triggers inflammation during normal immune responses; however, when overproduced, TNF can lead to excessive inflammation such as that experienced by patients with rheumatoid arthritis.
Rheumatoid arthritis causes chronic inflammation and degeneration of the joints, typically in the fingers, hands, feet, ankles, knees, and shoulders.
Therefore, two chronic rheumatic diseases, Rheumatoid Arthritis (RA) and Systemic Lupus Erythematosus (SLE), have been targeted for discussion due to their similarities on two counts: 1) both are similar in exhibiting symptoms of connective tissue diseases and 2) both are characterized as remitting-relapsing diseases with difficult diagnosis and unpredictable prognosis (Affleck, Tennen, Pfeiffer, & Fifield, 1987; Cornwell & Schmitt, 1990; Pollock, Christian, & Sands, 1990).
com/research/rrdcp2/global_rheumatoid) has announced the addition of the "Global Rheumatoid Arthritis Drug Pipeline Capsule - 2012 Update" report to their offering.
announced today that it will launch the anti-rheumatic agent Careram (iguratimod) in Japan on September 12 for the treatment of rheumatoid arthritis.