rheumatoid factor


Also found in: Dictionary, Thesaurus, Medical, Legal, Financial, Acronyms, Wikipedia.
Related to rheumatoid factor: rheumatoid arthritis

rheumatoid factor

[′rü·mə‚tȯid ‚fak·tər]
(immunology)
The immunoglobulin in the class IgM that is detected in the synovial fluid of individuals with rheumatoid arthritis.
References in periodicals archive ?
INDEX TERMS: anti-CCP; rheumatoid arthritis; rheumatoid factor.
There also was a trend that associated lower birth order and lower social class with a reduced likelihood of rheumatoid factor positivity in women.
We were able to show that the combination of smoking and lack of the GSTM1 gene was correlated with a greater likelihood to be rheumatoid factor positive, and the questionnaires and radiology studies confirmed that these same individuals have more advanced, more severe rheumatoid arthritis," Mattey says.
Rheumatoid factor and [beta]-human chorionic gonadotropin assays were both negative.
Rheumatoid factor was present in people aged 15-69 years and absent beyond 69 years.
CV was first described in 1966 by Meltzer and colleagues, who reported 29 patients with cryoglobulins and a common clinical presentation (purpura, arthralgias, and weakness), accompanied by organ dysfunction and raised serum concentrations of rheumatoid factor (3).
The new services aid the early diagnosis of RA, with one test service providing results of 14-3-3eta blood levels, while a comprehensive panel provides results of blood levels of 14-3-3eta as well as the conventional RA markers cyclic citrullinated peptide (CCP) antibodies and rheumatoid factor (RF).
Tests for rheumatoid factor (RF) proved of limited value because RF is not highly specific for RA.
At the time of the screening, eligible participants need to test positive for anti-CCP antibodies or rheumatoid factor.
London, September 7 ( ANI ): Researchers have found that men and women with raised levels of an antibody known as rheumatoid factor in their blood have up to a 26-fold greater long term risk of developing rheumatoid arthritis.
Among the baseline characteristics measured, including age, gender, disease duration, corticosteroid use, prior TNF inhibitor therapy, erythrocyte sedimentation rate (ESR), anticyclic citrulinated peptide (CCP) antibody level, only high titers of IgM rheumatoid factor (RF) correlated significantly with improved CDAI scores on tocilizumab therapy.

Full browser ?