rheumatoid nodules


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Related to rheumatoid nodules: rheumatoid arthritis, rheumatoid factor

rheumatoid nodules

[′rü·mə‚tȯid ′näj·ülz]
(medicine)
Subcutaneous lateral foci of fibrinoid degeneration or necrosis surrounded by mononuclear cells in a regular palisade arrangement, occurring usually in association with rheumatoid arthritis or rheumatic fever.
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Smoking: Even passive smokers are at risk of hearing impairment due to nicotine-related vasoconstriction (constriction of the blood vessels)--which results in a decrease in oxygen concentration, and which can harm external hair cells in the ear canal, resulting in declining cochlear function, causing SNHL RA smokers have increased risk of developing rheumatoid nodules and vasculitis.
The most common symptoms are tender, warm, swollen joints; symmetrical pattern of pain; joint inflammation; fatigue; occasional fever; a general sense of malaise; pain and stiffness lasting for more than 30 minutes in the morning or after a long rest; and rheumatoid nodules (bumps under the skin).
Rheumatoid nodules Size and degree of tenderness of subcutaneous nodules over bony prominences or tendons is variable Serum rheumatoid factor (RF) RF has low specificity for RA compared with anti-cyclic citrullinated peptide antibody (anti-CCP); although a positive anti-CCP test is not formally part of the diagnostic criteria, it should be part of a RA assessment Radiographic changes Usually of the hand or wrist; bony erosions and localized decalcifications are indicators of RA * RA diagnosis requires presence of [greater than or equal to]4 criteria.
1) RA is marked by several key characteristics, including synovitis occurring in a symmetrical fashion, polyarthritis, morning stiffness lasting over an hour, periods of disease flare-ups followed by periods of disease remission, and the development of subcutaneous rheumatoid nodules.
3) A more severe disease prognosis is associated with insidious onset in combination with symptoms such as weight loss, fatigue and low-grade fever, rapid appearance of rheumatoid nodules, and seropositivity for RF (often present at high titers).
The histologic characteristics of the lesions in our patient appeared to be the same as those of subcutaneous rheumatoid nodules.
VIENNA -- Early rheumatoid nodules, pulmonary involvement, and malaise with weight loss are predictive of long-term poor outcomes in rheumatoid arthritis, Gouri Koduri, M.
Rather, the lesions were likely rheumatoid nodules.
The discovery of rheumatoid nodules, for example, may be an important clue.
Rheumatoid nodules are hard nodules that frequently form directly over bony prominences in people with rheumatoid arthritis.
9 The presence of rheumatoid factor positivity and rheumatoid nodules had no significant correlation with carotid intima media thickness.
About 20 percent of people with RA develop rheumatoid nodules.