Kim, "Highly efficient RNA-guided genome editing in human cells via delivery of purified Cas9 ribonucleoproteins
," Genome Research, vol.
immunoprecipitated LINE-1 ribonucleoproteins
by using FLAG-tagged ORF1p or ORF2p and found that L1 RNA represented 8.3%-10.3% and 18.0%-28.2% of reads associated with ORF1p pulldown or ORF2p pulldown, respectively (31).
PTB protein forms ribonucleoprotein
complexes with PSF, hnRNPL, and other proteins to regulate the gene expression, stability, and localization of mRNA during apoptosis.
TIA-1 and TIAR regulate alternative splicing, SG formation, and translation of various target genes including TNF[alpha], COX-2, c-myc, calmodulin 2, small nuclear ribonucleoprotein
polypeptide F (SNRPF), and caspase-8 in response to various cellular stresses .
EIciRNAs are also abundant in nucleus, such as circEIF3J and circPAIP2, and can bind to U1 snRNP (small nuclear ribonucleoproteins
) in nucleus to form EIciRNA-U1 snRNP complexes.
• RNP- Deliver Cas9/guide RNA ribonucleoprotein
Tudor staphylococcal nuclease (Tudor-SN) participates in small ribonucleoprotein
(snRNP) assembly via interacting with symmetrically dimethylated Sm proteins.
Antinuclear antibodies (ANA), anti-double strain DNA antibodies (anti-ds DNA), anti-topoisomerase I antibodies (anti-SCL70), anti-U1 ribonucleoprotein
antibodies (anti-U1 RNP), serum 25-OH vitamin D level, blood tryptase level, angiotensin converting enzyme (ACE) levels, 24-hour urine volume, urinary Na, and vanillylmandelic acid concentration tests were performed to exclude differential diagnosis.
Mercuric chloride induces autoantibodies against U3 small nuclear ribonucleoprotein
in susceptible mice.
These proteins include ELAV-like protein 1 (ELAVL1), heterogeneous nuclear ribonucleoprotein
A1 isoforms a and b (HNRNPA1) and heterogeneous nuclear ribonudeoproteins A2/B1 isoforms A2 and B1 (HNRNPA2B1).
Rearrangement of nuclear ribonucleoprotein
(RNP)-containing structures during apoptosis and transcriptional arrest.
Telomerase is a ribonucleoprotein
that consists of two central components: a protein reverse transcriptase component (TERT) and an RNA template (TERC).