rifampicin


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Related to rifampicin: ethambutol, Pyrazinamide

rifampicin

[rə′fam·pə·sən]
(microbiology)
An antibacterial and antiviral antibiotic; action depends upon its preferential inhibition of bacterial ribonucleic acid polymerase over animal-cell RNA polymerase.
References in periodicals archive ?
Since in GeneXpert only rifampicin resistance is reported so for the isoniazid resistance normal DST was performed.
Rifampicin was measured by high-performance liquid chromatography using a Flexar[R] system (Perkin Elmer), after liquid-liquid extraction from plasma, following the procedure proposed by Zhou et al.
High prevalence of multidrug-resistant tuberculosis among patients with rifampicin resistance using GeneXpert Mycobacterium tuberculosis/rifampicin in Ghana.
WHO estimates that in 2016 there were 600,000 new cases with resistance to rifampicin - the most effective first-line drug-of which 490,000 had MDR-TB.
Rifampicin reduces plasma concentrations of moxifloxacin in patients with tuberculosis.
Since the patient was not receiving any other medications implicated in hemolysis, Rifampicin was considered the likely culprit [4].
GeneXpert MTB/RIF detected an additional 2 patients with rifampicin resistance in which the culture results were negative (Table 2).
Out of 40, GeneXpert positive patients, Rifampicin resistance was detected in 2 patients (5%).
Detection of mycobacteria and Rifampicin resistance was carried-out in the same setting.
Stock solution of the drugs was prepared based on the potency of the drug in sterile distilled water for streptomycin, isoniazid and ethambutol and in absolute methanol for rifampicin. [9]
tuberculosis with available TB drug susceptibility tests results for at least isoniazid and rifampicin. In patients with multiple positive TB cultures, only the first positive culture was included.