salicylanilide

salicylanilide

[¦sal·ə·səl′an·əl·əd]
(pharmacology)
C13H11NO2 A crystalline compound with a melting point of 135.8-136.2°C; freely soluble in alcohol, ether, chloroform, and benzene, slightly soluble in water; used as a topical antifungal agent in humans and animals and in medicine.
References in periodicals archive ?
Vanco et al., "Acetylcholinesterase-inhibiting activity of salicylanilide N-alkylcarbamates and their molecular docking," Molecules, vol.
The fungitoxicity of 4- and 5- alkyl salicylanilide and p-chloroanilines.
Recently, salicylanilide diethyl phosphates (diethyl [(2-phenylcarbamoyl)phenyl] phosphates 1; Figure 1) have been synthesized as potential antimycobacterial agents with activity in the micromolar range (minimum inhibitory concentrations (MICs) from 1 [micro]M).
Based on the fact that salicylanilides and their esters with various acids have been reported as isocitrate lyase inhibitors [3, 5], we evaluated salicylanilide diethyl phosphates 1 against this enzyme (Table 1).
Several investigators have synthesized AChE inhibitors like alkylpyridium polymers [19], dehydroevodiamine (DHED) [20], N-arylsubstituted succinimides [21], lycorine derivatives [22], salicylanilide N-alkylcarbamates [23], and 7-methoxytacrineadamantylamine heterodimers [24].
On sum up, ligand K bonds only to the PAS site like the known allosteric inhibitors decidium (DI), propidium (PI), ethidium, and gallamine (GAL) [36-38, 48] salicylanilide N-Alkylcarbamates [23].
Toxicity of three candidate nonoxidizing molluscicides: TFM, Bayer 73 and salicylanilide I to zebra mussels (Dreissena polymorpha) and quagga mussels (D.
Photo allergens After radiation Tetrachloro salicylanilide + Chlorhexidine + Triclosan + Methylcoumarin + Musk ambrette + Thiourea + Isoamyl p-methoxycinnamate + Ethylhexyl p-methoxycinnamate + Benzophenone 4 + Oxybenzone + 4-tert-butyl-4'-methoxy-dibenzoylmethane + Benzydamine + Sulfanilamide + Chlorpromazine + Promethazine + Hydrochlorothiazide + Carbamazepine + Piroxicam + Lichen acid mix + P-aminobenzoic acid + + = positive irradiated photo-epicutaneous test Discussion
This phenomenon seems to play a role in photosensitivity maintenance, particularly in cases involving certain classical allergens that have a high phototoallergic poten-tial, such as tetrachloro salicylanilide, musk ambrette, sulfanila-mide, lichen acid mix, and P-aminobenzoic acid (5), (9).
The ineffectiveness of Rafoxanide (3,5-diiodo 3' chlor 4'-(PChlorophenoxi) salicylanilide) against Platynosomum fastosum, The liver fluke of domestic cats.
Jampilek, "Salicylanilide esters of N-protected amino acids as novel antimicrobial agents," Bioorganic and Medicinal Chemistry Letters, vol.
Ferriz et al., "New antituberculotics originated from salicylanilides with promising in vitro activity against atypical mycobacterial strains," Bioorganic and Medicinal Chemistry, vol.