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The thin connective tissue sheath enveloping a muscle fiber.



the delicate membrane that invests smooth-muscle cells and striated and myocardial fibers. The term “sar-colemma” was introduced by the British physician W. Bowman in 1840. A sarcolemma consists of a three-layer cell membrane, which is approximately 75 angstroms thick and similar to the cell membrane in other animal cells, and a basilar membrane, which is a layer of amorphous matter containing polysaccharides. In vertebrates the basilar membrane of muscle cells and muscle fibers usually contains collagen fibrils.


De Robertis, E., W. Nowinski, and F. Saez. Biologiia kletki. Moscow, 1967. (Translated from English.)
Elektronno-mikroskopicheskaia anatomiia. Moscow, 1967. (Translated from English.)
References in periodicals archive ?
Petrof, "Sarcolemmal damage in dystrophin deficiency is modulated by synergistic interactions between mechanical and oxidative/nitrosative stresses," The American Journal of Pathology, vol.
In skeletal muscle, X-ROS sensitizes [Ca.sup.2+]-permeable sarcolemmal "transient receptor potential" (TRP) channels, a pathway critical for sustaining SR load during repetitive contractions.
Lakatta, "Synergism of coupled subsarcolemmal [Ca.sup.2+] clocks and sarcolemmal voltage clocks confers robust and flexible pacemaker function in a novel pacemaker cell model," American Journal of Physiology, vol.
It describes that strenuous physical exercise, may cause muscle injury and results in rupture of sarcolemmal membrane and cause muscle proteins (such as CK and Mb) leakage into the bloodstream.
Vetter, "Thyroid control of sarcolemmal [Na.sup.+]/[Ca.sup.2+] exchanger and SR [Ca.sup.2+]-ATPase in developing rat heart," American Journal of Physiology, vol.
(3,6) Current research suggests that several factors play a role in the development of rhabdomyolysis, such as decreased protein synthesis and sarcolemmal excitability, increased protein degradation, modifications in carbohydrate metabolism, mitochondrial changes and electrolyte disturbances.
Cardiac sarcolemmal Na+-Ca2+ exchange and Na+-K+ ATPase activities and gene expression in alloxan-induced diabetes in rats.
Myocyte apoptosis during acute myocardial infarction in rats is related to early sarcolemmal translocation of annexin A5 in border zone.
2002 Temperature dependent expression of sarcolemmal K currents in rainbow trout atrial and ventricular myocytes.