sarcoplasmic reticulum


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sarcoplasmic reticulum

[¦sar·kə¦plaz·mik rə′tik·yə·ləm]
(cell and molecular biology)
Collectively, the cysternae of a single muscle fiber.
References in periodicals archive ?
In heart, X-ROS acts locally to affect the sarcoplasmic reticulum (SR) [Ca.
Although there has been little investigation into the cardioprotective effects of intravenous anaesthetics such as ketamine and benzodiazepines, propofol has been shown to demonstrate some cardioprotective effects (34), possibly by affecting sarcoplasmic reticulum [Ca.
Porcine stress syndrome (PSS) susceptibility, has been associated with a single point mutation C1843T (Arg615Cys) in the Ca2+ release channel at the sarcoplasmic reticulum ryanodine receptor 1 (RYR1).
1,2,4,5) Dantrolene can be used to reduce both core body temperature and peripheral muscle rigidity by inhibiting calcium release from the muscle sarcoplasmic reticulum.
Because the T tubules of the sarcoplasmic reticulum are formed by the infolding of the cell membrane, extracellular calcium can enter the T tubules and stimulate the sarcoplasmic reticulum to release calcium, thus improving the contractility of the myocardium (Proano, Chiang, and Wang, 1995).
RyRs share a common molecular morphology, with a "foot" structure bridging the junctional gap between sarcoplasmic reticulum and plasma membrane (1).
Cytoplasmic organelles, such as mitochondria with cristae mitochondriales and sarcoplasmic reticulum, were cleary seen in three-dimensional HRSEM images
Vacuolar degeneration is characterized by distention of the sarcoplasmic reticulum and T-tubular system, leading to large membrane-bound vacuoles.
A research team led by Roger Hajjar, MD of Massachusetts General Hospital in Boston used an adenoviral gene vector to overexpress the sarcoplasmic reticulum calcium ATPase (SERCA2a) pump in ventricular myocytes taken from the explanted hearts of 5 patients with ischemic cardiomyopathy, 5 with dilated cardiomyopathy, and from 3 healthy donor hearts.
sup][22],[23] Sarcoplasmic reticulum (SR)/ER calcium ATPases (SERCAs) are calcium pumps that couple ATP hydrolysis with calcium transport across the SR/ER membrane.