The liver was characterized by the presence of a few schizonts
in hepatocytes and endothelial cells and a very large number of macrophages filled by characteristically shaped basophilic merozoites contained in parasitophorous vacuoles, a typical invagination of the cytoplasmic membrane of host cells that surround the parasites.
Tissue damage in cattle infected with Theileria annulata accompanied by metastasis of cytokine producing, schizont
infected mononuclear phagocytes.
This implies that the number of secondary infections during malaria infections is largely influenced by the average number of merozoites released K, from a bursting blood schizont
, most of which are responsible for secondary infections at the blood stage.
At this stage, the targets are free merozoites and intraerythrocytic parasites (schizonts
Impact of field vaccination with a Theileria annulata schizont
cell culture vaccine on the epidemiology of tropical theileriosis.
The high concentration of DQ distributed in the liver is very important due to the obligate nature of liver schizont
growth which begins the complex life cycle of Plasmodium parasites.
All the terpenes tested inhibited dolichol biosynthesis in the trophozoite and schizont
When mouse bone marrow-derived dendritic cells (BMDDC) were stimulated with the same schizont
fraction, upregulated expressions of CD40, CD86, and IL-12 production were observed .
Giemsa stained thin blood films (Sysmex SP-1000i; Sysmex, Kobe, Japan; Roche, Basel, Switzerland) revealed enlarged oval and fimbriated red cells with trophozoite and schizont
forms of malarial parasites (Figures 4 and 5).
Thus, the first aim of this study was to determine the short-term antihelminthic effects on immunological markers of exposure to schistosome (IgM directed against schistosome cercariae, egg, and adult worms ) and malaria (IgM directed against Plasmodium total schizont
) infections as well as the effects on antibody responses associated with resistance to infection/reinfection (IgE and IgG4 directed against schistosome cercariae, egg, and adult worms, IgG directed against Plasmodium vaccine candidates MSP-1 and MSP-2 [16, 21-23]) in children aged 3-5 years in Zimbabwe.
If the sporozoite injected by a mosquito into a human host develops directly into a tissue schizont
, the incubation period between the initial infection and the onset of symptoms is short, typically from 10 days to 4 weeks, resulting in an early primary attack.
(11) Those which escape destruction invade the hepatocytes and start heavily replicating, passing through the schizont
and the merozoite stages.